The past decade has witnessed a consolidation and refinement of the extraordinary
progress made in taste research. This Review describes recent advances in our …

Olfactory and taste receptors are expressed primarily in the nasal olfactory epithelium and
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …

Bitter taste-sensing type 2 receptors (TAS2Rs or T2Rs), belonging to the subgroup of family
A G-protein coupled receptors (GPCRs), are of crucial importance in the perception of …

The present review examines the pig as a model for physiological studies in human subjects
related to nutrient sensing, appetite regulation, gut barrier function, intestinal microbiota and …

Bitter taste receptors (TAS2Rs or T2Rs) belong to the superfamily of seven-transmembrane
G protein–coupled receptors, which are the targets of> 50% of drugs currently on the market …

The perception of sweet taste is mediated by the T1R2/T1R3 receptor, which is expressed in
the oral cavity, wherein it provides input on the caloric and macronutrient contents of …

MyoD, Myf5, myogenin, and MRF4 (also known as Myf6 or herculin) are myogenic
regulatory factors (MRFs). MRFs are regarded as master transcription factors that are …

One key to animal survival is the detection and avoidance of potentially harmful compounds
by their bitter taste. Variable numbers of taste 2 receptor genes expressed in the gustatory …

Bitter taste is an innately aversive taste modality that is considered to protect animals from
consuming toxic compounds. Yet, bitterness is not always noxious and some bitter …

Humans can recognise five basic tastes: sweet, sour, salty, bitter and umami. Sour and salty
substances are linked to ion channels, while sweet, bitter and umami flavours are …