HVYWMOMLDIMFJA-DPAQBDIFSA-N (3β)-Cholest-5-en-3-ol Chemical compound C1C=
C2C [C@@ H](O) CC [C@] 2 (C)[C@@ H] 2 [C@@ H] 1 [C@@ H] 1CC [C@ H]([C@ H](C) …

Provided herein are methods of modulating bile acid homeostasis or treating a bile-acid
related or associated disorder, comprising using variants and fusions of fibroblast growth …

US9580483B2 - Methods of using compositions comprising variants and fusions of FGF19
polypeptides for treatment of diabetes - Google Patents US9580483B2 - Methods of using …

HDTRYLNUVZCQOY-LIZSDCNHSA-N Trehalose Chemical compound O [C@@ H] 1 [C@@
H](O)[C@ H](O)[C@@ H](CO) O [C@@ H] 1O [C@@ H] 1 [C@ H](O)[C@@ H](O)[C …

Bile acids, steroid acids that are found predominantly in the bile of mammals, regulate
cholesterol, triglyceride, glucose and energy homeostasis, and facilitate digestion and …

US9670260B2 - Compositions comprising fusion variants of FGF19 polypeptides - Google
Patents US9670260B2 - Compositions comprising fusion variants of FGF19 polypeptides …

The invention relates to variants and fusions of fibroblast growth factor 19 (FGF19), variants
and fusions of fibroblast growth factor 21 (FGF21), fusions of FGF19 and/or FGF21, and …

US9089525B1 - Methods of using compositions comprising variants and fusions of FGF19
polypeptides for reducing glucose levels in a subject - Google Patents US9089525B1 - Methods …

US9751924B2 - Methods of using compositions comprising fusion variants of FGF19
polypeptides for reducing glucose levels in a subject - Google Patents US9751924B2 - Methods …

The invention provides monoclonal antibodies that specifically bind to TIGIT. The
monoclonal antibodies have the capacity for substantial activation of T cells and natural …