A comprehensive update on the human leukocyte antigen and idiosyncratic adverse drug reactions

AA Elzagallaai, AM Abuzgaia… - Expert Opinion on Drug …, 2025 - Taylor & Francis
Introduction. Idiosyncratic adverse drug reactions (IADRs) or drug hypersensitivity reactions
(DHRs) represent a major health problem because they are unpredictable and can be …

Allopurinol-Induced Severe Cutaneous Adverse Reactions in Vietnamese: The Role of HLA Alleles and Other Risk Factors

TT Ha Pham, QB Tran, CH Chu, TQ Nga Do… - …, 2022 - Taylor & Francis
Aim: To reveal the association of three class I HLA alleles, including HLA-A* 33: 03, HLA-B*
58: 01 and HLA-C* 03: 02, and allopurinol-induced severe cutaneous adverse reactions …