Predictive and prognostic biomarkers in colorectal cancer: A systematic review of recent advances and challenges

V Das, J Kalita, M Pal - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Background Colorectal cancer (CRC) is one of the leading cause of cancer deaths
worldwide. Since CRC is largely asymptomatic until alarm features develop to advanced …

[HTML][HTML] Genetic and epigenetic biomarkers for diagnosis, prognosis and treatment of colorectal cancer

F Coppedè, A Lopomo, R Spisni… - World journal of …, 2014 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most common cancer worldwide and results from the
accumulation of mutations and epimutations in colonic mucosa cells ultimately leading to …

Perineural invasion is a strong prognostic factor in colorectal cancer: a systematic review

N Knijn, SC Mogk, S Teerenstra, F Simmer… - The American journal …, 2016 - journals.lww.com
Perineural invasion (PNI) is a possible route for metastatic spread in various cancer types,
including colorectal cancer (CRC). PNI is linked to poor prognosis, but systematic analyses …

Centyrin ligands for extrahepatic delivery of siRNA

D Klein, S Goldberg, CS Theile, R Dambra, K Haskell… - Molecular Therapy, 2021 - cell.com
RNA interference (RNAi) offers the potential to treat disease at the earliest onset by
selectively turning off the expression of target genes, such as intracellular oncogenes that …

Antiproliferative, antiangiogenic, and antimetastatic therapy response by mangiferin in a syngeneic immunocompetent colorectal cancer mouse model involves …

JC Rodriguez-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
In spite of the current advances and achievements in cancer treatments, colorectal cancer
(CRC) persists as one of the most prevalent and deadly tumor types in both men and women …

Identification of APC mutation as a potential predictor for immunotherapy in colorectal cancer

F Feng, H Sun, Z Zhao, C Sun, Y Zhao, H Lin… - Journal of …, 2022 - Wiley Online Library
To date, anticancer immunotherapy has presented some clinical benefits to most of
advanced mismatch repair deficient (dMMR)/microsatellite instability‐high (MSI‐H) …

Wnt signaling pathway pharmacogenetics in non-small cell lung cancer

DJ Stewart, DW Chang, Y Ye, M Spitz, C Lu… - The …, 2014 - nature.com
Abstract Wingless-type protein (Wnt)/β-catenin pathway alterations in non-small cell lung
cancer (NSCLC) are associated with poor prognosis and resistance. In 598 stage III–IV …

Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?

J Roos, S Grösch, O Werz, P Schröder, S Ziegler… - Pharmacology & …, 2016 - Elsevier
Canonical Wnt signaling is a highly conserved pathway with a prominent role in
embryogenic development, adult tissue homeostasis, cell polarization, stem cell biology, cell …

[HTML][HTML] Ginsenoside Rh1 inhibits colorectal cancer cell migration and invasion in vitro and tumor growth in vivo

X Lyu, X Xu, A Song, J Guo, Y Zhang… - Oncology …, 2019 - spandidos-publications.com
Colorectal cancer (CRC) is the third leading cause of cancer‑associated mortality worldwide.
Ginsenoside Rh1 (Rh1) is a traditional medicine monomer with antitumor activity; however …

RETRACTED ARTICLE: Long Non-Coding RNA LEF1-AS1 Promotes Migration, Invasion and Metastasis of Colon Cancer Cells Through miR-30-5p/SOX9 Axis

T Sun, Z Liu, R Zhang, S Ma, T Lin, Y Li… - OncoTargets and …, 2020 - Taylor & Francis
Sun T, Liu Z, Zhang R, et al. Onco Targets Ther. 2020; 13: 2957-2972. We, the Editors and
Publisher of OncoTargets and Therapy, have retracted the following article. Concerns were …