Regulation of blood flow in the retinal trilaminar vascular network

TE Kornfield, EA Newman - Journal of Neuroscience, 2014 - Soc Neuroscience
Light stimulation evokes neuronal activity in the retina, resulting in the dilation of retinal
blood vessels and increased blood flow. This response, named functional hyperemia, brings …

Potential mechanisms of retinal ganglion cell type‐specific vulnerability in glaucoma

AYM Wang, PY Lee, BV Bui, AI Jobling… - Clinical and …, 2020 - Taylor & Francis
Glaucoma is a neurodegenerative disease characterised by progressive damage to the
retinal ganglion cells (RGCs), the output neurons of the retina. RGCs are a heterogenous …

[HTML][HTML] Nonvascular retinal imaging markers of preclinical Alzheimer's disease

PJ Snyder, LN Johnson, YY Lim, CY Santos… - Alzheimer's & Dementia …, 2016 - Elsevier
Abstract Introduction In patients with Alzheimer's disease (AD) and mild cognitive
impairment, structural changes in the retina (ie, reduced thicknesses of the ganglion cell and …

Of neurons and pericytes: The neuro-vascular approach to diabetic retinopathy

CG Eleftheriou, E Ivanova, BT Sagdullaev - Visual Neuroscience, 2020 - cambridge.org
Diabetic retinopathy (DR) is a frequent complication of diabetes mellitus and an increasingly
common cause of visual impairment. Blood vessel damage occurs as the disease …

[HTML][HTML] Emerging strategies targeting genes and cells in glaucoma

S Roy - Vision Research, 2025 - Elsevier
Glaucoma comprises a heterogeneous set of eye conditions that cause progressive vision
loss. Glaucoma has a complex etiology, with different genetic and non-genetic risk factors …

Domain‐specific distribution of gap junctions defines cellular coupling to establish a vascular relay in the retina

E Ivanova, T Kovacs‐Oller… - Journal of Comparative …, 2019 - Wiley Online Library
In the retina, diverse functions of neuronal gap junctions (GJs) have been established.
However, the distribution and function of vascular GJs are less clear. Here in the mouse …

[HTML][HTML] Mapping the 3D connectivity of the rat inner retinal vascular network using OCT angiography

C Leahy, H Radhakrishnan, G Weiner… - … & visual science, 2015 - arvojournals.org
Purpose: The purpose of this study is to demonstrate three-dimensional (3D) graphing
based on optical coherence tomography (OCT) angiography for characterization of the inner …

Retinal vascular remodeling in photoreceptor degenerative disease

M Nguyen, J Sullivan, W Shen - Experimental Eye Research, 2023 - Elsevier
Abnormal vasculature in the retina, specifically tortuous vessels and capillary degeneration,
is common in many of the most prevalent retinal degenerative diseases, currently affecting …

Retinal ganglion cell dysfunction in mice following acute intraocular pressure is exacerbated by P2X7 receptor knockout

AYM Wang, VHY Wong, PY Lee, BV Bui, S Dudczig… - Scientific reports, 2021 - nature.com
There is increasing evidence for the vulnerability of specific retinal ganglion cell (RGC) types
in those with glaucoma and in animal models. In addition, the P2X7-receptor (P2X7-R) has …

Increased phosphorylation of Cx36 gap junctions in the AII amacrine cells of RD retina

E Ivanova, CW Yee, BT Sagdullaev - Frontiers in cellular …, 2015 - frontiersin.org
Retinal degeneration (RD) encompasses a family of diseases that lead to photoreceptor
death and visual impairment. Visual decline due to photoreceptor cell loss is further …