[HTML][HTML] Cyclin-dependent kinases and CDK inhibitors in virus-associated cancers
S Tavakolian, H Goudarzi, E Faghihloo - Infectious Agents and Cancer, 2020 - Springer
The role of several risk factors, such as pollution, consumption of alcohol, age, sex and
obesity in cancer progression is undeniable. Human malignancies are mainly characterized …
obesity in cancer progression is undeniable. Human malignancies are mainly characterized …
Retinoic acid induced mitogen-activated protein (MAP)/extracellular signal-regulated kinase (ERK) kinase-dependent MAP kinase activation needed to elicit HL-60 …
A Yen, MS Roberson, S Varvayanis, AT Lee - Cancer research, 1998 - AACR
Retinoic acid (RA) activated the extracellular signal-regulated kinase (ERK) 2 mitogen-
activated protein kinase (MAPK) of HL-60 human myeloblastic leukemia cells before …
activated protein kinase (MAPK) of HL-60 human myeloblastic leukemia cells before …
[HTML][HTML] Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the …
KJ Townsend, P Zhou, L Qian, CK Bieszczad… - Journal of Biological …, 1999 - ASBMB
Proliferation, differentiation, and apoptosis are tightly regulated during hematopoiesis,
allowing amplification along specific lineages while preventing excessive proliferation of …
allowing amplification along specific lineages while preventing excessive proliferation of …
Natural variants of hepatitis B virus X protein have differential effects on the expression of cyclin‐dependent kinase inhibitor p21 gene
HJ Kwun, KL Jang - Nucleic acids research, 2004 - academic.oup.com
Despite the extensive studies on the roles of hepatitis B virus X protein (HBx), the effects of
HBx on the important cellular processes such as cell growth, cell transformation and …
HBx on the important cellular processes such as cell growth, cell transformation and …
Dual effects of hepatitis B virus X protein on the regulation of cell-cycle control depending on the status of cellular p53
JY Ahn, EY Jung, HJ Kwun, CW Lee… - Journal of General …, 2002 - microbiologyresearch.org
Despite the extensive studies on the roles of hepatitis B virus (HBV) X protein (HBx) in the
development of hepatocellular carcinomas (HCCs), the mechanisms by which HBx …
development of hepatocellular carcinomas (HCCs), the mechanisms by which HBx …
Retinoic acid causes MEK-dependent RAF phosphorylation through RARα plus RXR activation in HL-60 cells
HY Hong, S Varvayanis, A Yen - Differentiation, 2001 - Elsevier
Retinoic acid (RA) is known to cause the myeloid differentiation of HL-60 human
myeloblastic leukemia cells in a process requiring MEK-dependent ERK2 activation. This …
myeloblastic leukemia cells in a process requiring MEK-dependent ERK2 activation. This …
Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells
J Smith, RP Bunaciu, G Reiterer, D Coder… - Experimental cell …, 2009 - Elsevier
All trans-retinoic acid (RA) is a standard therapeutic agent used in differentiation induction
therapy treatment of acute promyelocytic leukemia (APL). RA and its metabolites use a …
therapy treatment of acute promyelocytic leukemia (APL). RA and its metabolites use a …
Human myeloblastic leukemia cells (HL-60) express a membrane receptor for estrogen that signals and modulates retinoic acid-induced cell differentiation
MA Kauss, G Reiterer, RP Bunaciu, A Yen - Experimental cell research, 2008 - Elsevier
Estrogen receptors are historically perceived as nuclear ligand activated transcription
factors. An estrogen receptor has now been found localized to the plasma membrane of …
factors. An estrogen receptor has now been found localized to the plasma membrane of …
Retinoic acid increases amount of phosphorylated RAF; ectopic expression of cFMS reveals that retinoic acid-induced differentiation is more strongly dependent on …
A Yen, R Sturgill, S Varvayanis - In Vitro Cellular & Developmental Biology …, 2000 - Springer
Retinoic acid is known to cause the myeloid differentiation and G1/0 cell cycle arrest of HL-
60 cells in a process that requires mitogen-activated protein/extracellular signal regulated …
60 cells in a process that requires mitogen-activated protein/extracellular signal regulated …
Retinoic acid induces expression of SLP-76: expression with c-FMS enhances ERK activation and retinoic acid-induced differentiation/G0 arrest of HL-60 cells
A Yen, S Varvayanis, JL Smith, TJ Lamkin - European journal of cell biology, 2006 - Elsevier
Retinoic acid (RA) is known to cause MAPK signaling which propels G0 arrest and myeloid
differentiation of HL-60 human myeloblastic leukemia cells. The present studies show that …
differentiation of HL-60 human myeloblastic leukemia cells. The present studies show that …