The fascinating patterns of collective motion created by autonomously driven particles have
fuelled active-matter research for over two decades. So far, theoretical active-matter …

The growth and survival of cells within tissues can be affected by 'cell competition'between
different cell clones. This phenomenon was initially recognized between wild-type cells and …

Despite acting as a barrier for the organs they encase, epithelial cells turn over at some of
the fastest rates in the body. However, epithelial cell division must be tightly linked to cell …

Cell motion inside dense tissues governs many biological processes, including embryonic
development and cancer metastasis, and recent experiments suggest that these tissues …

E-cadherin is a transmembrane glycoprotein which connects epithelial cells together at
adherens junctions. In normal cells, E-cadherin exerts its tumour suppressing role mainly by …

Tissue, cell, and nucleus morphology change during tumor progression. In 2D confluent cell
cultures, different tissue states, such as fluid (unjammed) and solid (jammed), are correlated …

Modulating signaling pathways including Wnt and Hippo can induce cardiomyocyte
proliferation in vivo. Applying these signaling modulators to human induced pluripotent stem …

To perceive their three-dimensional environment, cells and tissues must be able to sense
and interpret various physical forces like shear, tensile, and compression stress. These …

Cancer cell migration and invasion are integral components of metastatic disease, which is
the major cause of death in cancer patients. Cancer cells can disseminate and migrate via …

Signalling from the extracellular matrix (ECM) is a fundamental cellular input that sustains
proliferation, opposes cell death and regulates differentiation. Through integrins, cells …