[HTML][HTML] Advances in aptameric biosensors designed to detect toxic contaminants from food, water, human fluids, and the environment

US Kadam, JC Hong - Trends in Environmental Analytical Chemistry, 2022 - Elsevier
Detection of toxic small molecule contaminants with sensitivity, accuracy, and specificity is a
challenging task. Traditionally used HPLC and mass spectrometry-based assays suffer from …

Aptamer-based CRISPR-Cas powered diagnostics of diverse biomarkers and small molecule targets

US Kadam, Y Cho, TY Park, JC Hong - Applied Biological Chemistry, 2023 - Springer
CRISPR-Cas systems have been widely used in genome editing and transcriptional
regulation. Recently, CRISPR-Cas effectors are adopted for biosensor construction due to its …

Assessment of genetic diversity and volatile content of commercially grown banana (Musa spp.) cultivars

VR Hinge, IM Shaikh, RL Chavhan, AS Deshmukh… - Scientific Reports, 2022 - nature.com
Banana is an important fruit crop in the tropics and subtropics; however, limited information
on biomarkers and signature volatiles is available for selecting commercial cultivars. Clonal …

METTL5-mediated 18S rRNA m6A modification promotes oncogenic mRNA translation and intrahepatic cholangiocarcinoma progression

Z Dai, W Zhu, Y Hou, X Zhang, X Ren, K Lei, J Liao… - Molecular Therapy, 2023 - cell.com
Intrahepatic cholangiocarcinoma (ICC) is a deadly cancer with rapid tumor progression.
While hyperactive mRNA translation caused by mis-regulated mRNA or tRNA modifications …

[HTML][HTML] Identification and structural analysis of novel malathion-specific DNA aptameric sensors designed for food testing

US Kadam, KH Trinh, V Kumar, KW Lee, Y Cho… - Biomaterials, 2022 - Elsevier
Malathion is an organophosphate chemical (OPC) and a toxic contaminant that adversely
impacts food quality, human health, biodiversity, and the environment. Due to its small size …

[HTML][HTML] A comparative analysis of single-cell transcriptomic technologies in plants and animals

VR Netla, H Shinde, G Kumar, A Dudhate, JC Hong… - Current Plant …, 2023 - Elsevier
The development of sequencing methods has resulted in the investigation of many
unexplored research areas. Among the different sequencing methods, single-cell …

Concerns regarding 'off-target'activity of genome editing endonucleases

US Kadam, RM Shelake, RL Chavhan… - Plant Physiology and …, 2018 - Elsevier
Genome editing (GE) tools ensure targeted mutagenesis and sequence-specific
modification in plants using a wide resource of customized endonucleases; namely, zinc …

Novel DNA aptameric sensors to detect the toxic insecticide fenitrothion

KH Trinh, US Kadam, J Song, Y Cho, CH Kang… - International Journal of …, 2021 - mdpi.com
Fenitrothion is an insecticide belonging to the organophosphate family of pesticides that is
widely used around the world in agriculture and living environments. Today, it is one of the …

[HTML][HTML] Engineering novel aptameric fluorescent biosensors for analysis of the neurotoxic environmental contaminant insecticide diazinon from real vegetable and …

MHT Can, US Kadam, KH Trinh, Y Cho… - Frontiers in Bioscience …, 2022 - imrpress.com
Background: Diazinon is a widely used organophosphorus neurotoxic insecticide. It is a
common environmental contaminant and a hazardous agri-waste. Its detection is critical to …

Population Genetics, Genetic Structure, and Inbreeding of Commiphora gileadensis (L.) C. Chr Inferred from SSR Markers in Some Mountainous Sites of Makkah …

H Mansour, KH Alamer, ZM Al-Hasawi - Plants, 2023 - mdpi.com
Commiphora gileadensis (L.) C. Chr is a perennial plant existing mainly in the southern and
western mountains of the Arabian Peninsula. In the Makkah province, the remaining …