Fundus-controlled perimetry (FCP, also called 'microperimetry') allows for spatially-resolved
mapping of visual sensitivity and measurement of fixation stability, both in clinical practice as …

Blindness, although not life threatening, is a debilitating disorder for which few, if any
treatments exist. Ocular gene therapies have the potential to profoundly improve the quality …

Leber congenital amaurosis (LCA) is a rare hereditary retinal degeneration caused by
mutations in more than a dozen genes. RPE65, one of these mutated genes, is highly …

Retinal pigment epithelial (RPE) transplantation aims to restore the subretinal anatomy and
re-establish the critical interaction between the RPE and the photoreceptor, which is …

Low vision rehabilitation is a new emerging subspecialty drawing from the traditional fields
of ophthalmology, optometry, occupational therapy, and sociology, with an ever-increasing …

The aim of this study was to explore the plasticity of fixation in patients with central vision
loss. Most of these patients use preferred retinal loci (PRLs) in the healthy eccentric part of …

The central region of the human retina, the fovea, provides high-acuity vision. The
oculomotor system continually brings targets of interest into the fovea via ballistic eye …

Purpose: The authors examined the fixation stability patterns of people with age-related
macular degeneration (AMD) using the MP-1 microperimeter and describe a method to …

Background: Eccentric viewing in macular disease has been described for half a century.
However, a clear definition of eccentric viewing and preferred retinal locus (PRL) does not …

In healthy vision, the fovea provides high acuity and serves as the locus for fixation achieved
through saccadic eye movements. Bilateral loss of the foveal regions in both eyes causes …