▪ Abstract Cyclin-dependent kinases (Cdks) play a well-established role in the regulation of
the eukaryotic cell division cycle and have also been implicated in the control of gene …

SUMMARY A cascade of three protein kinases known as a mitogen-activated protein kinase
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …

Nuclear factor κB (NF-κB) is an antiapoptotic transcription factor. We show that the
antiapoptotic actions of NF-κB are mediated by hydrogen sulfide (H 2 S) synthesized by …

In eukaryotic cells, incorrectly folded proteins in the endoplasmic reticulum (ER) are
exported into the cytosol and degraded by the proteasome. This pathway is co-opted by …

The stomatal pores of higher plants allow for gaseous exchange into and out of leaves.
Situated in the epidermis, they are surrounded by a pair of guard cells which control their …

The general transcription factors of RNA polymerase II. Publisher Logo Genes &
Development Skip to main page content HOME ABOUT SUBMIT SUBSCRIBE ADVERTISE …

The cyclin dependent kinase Cdk1 controls the cell cycle, which is best understood in the
model organism S. cerevisiae. Research performed during the past decade has significantly …

Transcription initiation by RNA polymerase II (RNA pol II) requires interaction between cis-
acting promoter elements and trans-acting factors. The eukaryotic promoter consists of core …

The cyclin-dependent protein kinase (CDK) encoded by CDC28 is the master regulator of
cell division in the budding yeast Saccharomyces cerevisiae. By mechanisms that, for the …

In metazoans, cyclin-dependent kinase 7 (CDK7) has essential roles in both the cell-division
cycle and transcription, as a CDK-activating kinase (CAK) and as a component of the …