[HTML][HTML] The chronic mild stress (CMS) model of depression: History, evaluation and usage

P Willner - Neurobiology of stress, 2017 - Elsevier
Now 30 years old, the chronic mild stress (CMS) model of depression has been used in>
1300 published studies, with a year-on-year increase rising to> 200 papers in 2015. Data …

Deep brain stimulation for treatment-resistant depression: an integrative review of preclinical and clinical findings and translational implications

MP Dandekar, AJ Fenoy, AF Carvalho, JC Soares… - Molecular …, 2018 - nature.com
Although deep brain stimulation (DBS) is an established treatment choice for Parkinson's
disease (PD), essential tremor and movement disorders, its effectiveness for the …

Wireless, battery-free, and fully implantable electrical neurostimulation in freely moving rodents

A Burton, SM Won, AK Sohrabi, T Stuart… - Microsystems & …, 2021 - nature.com
Implantable deep brain stimulation (DBS) systems are utilized for clinical treatment of
diseases such as Parkinson's disease and chronic pain. However, long-term efficacy of DBS …

Deep brain stimulation of the “medial forebrain bundle”: a strategy to modulate the reward system and manage treatment-resistant depression

AJ Fenoy, J Quevedo, JC Soares - Molecular Psychiatry, 2022 - nature.com
The medial forebrain bundle—a white matter pathway projecting from the ventral tegmental
area—is a structure that has been under a lot of scrutinies recently due to its implications in …

Brain mechanisms mediating effects of stress on reward sensitivity

M Ironside, P Kumar, MS Kang, DA Pizzagalli - Current opinion in …, 2018 - Elsevier
Highlights•Stress preferentially perturbates reward anticipation (rather than
consumption).•Cortico–striatal–limbic network dysregulation subserves stress effects on …

The medial forebrain bundle as a target for deep brain stimulation for obsessive-compulsive disorder

VA Coenen, TE Schlaepfer, P Goll, PC Reinacher… - CNS …, 2017 - cambridge.org
Deep brain stimulation (DBS) is a promising putative modality for the treatment of refractory
psychiatric disorders such as major depression and obsessive-compulsive disorder (OCD) …

[HTML][HTML] Serendipity and observations in functional neurosurgery: from James Parkinson's stroke to Hamani's & Lozano's flashbacks

M Hariz, AJ Lees, Y Blomstedt… - Stereotactic and functional …, 2022 - karger.com
Background: Serendipity and observations have a noble tradition in medicine, including
neurology, and are responsible for many medical treatments (carbamazepine for tic …

Neuromodulation in psychiatric disorders: experimental and clinical evidence for reward and motivation network deep brain stimulation: focus on the medial forebrain …

MD Döbrössy, C Ramanathan… - European Journal of …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) in psychiatric illnesses has been clinically tested over the past
20 years. The clinical application of DBS to the superolateral branch of the medial forebrain …

[HTML][HTML] Mood disturbances in Parkinson's disease: From prodromal origins to application of animal models

S Hayley, F Vahid-Ansari, H Sun, PR Albert - Neurobiology of Disease, 2023 - Elsevier
Parkinson's disease (PD) is a complex illness with a constellation of environmental insults
and genetic vulnerabilities being implicated. Strikingly, many studies only focus on the …

What can rodent models tell us about apathy and associated neuropsychiatric symptoms in Parkinson's disease?

R Magnard, Y Vachez, C Carcenac, P Krack… - Translational …, 2016 - nature.com
In addition to classical motor symptoms, Parkinson's disease (PD) patients display
incapacitating neuropsychiatric manifestations, such as apathy, anhedonia, depression and …