Evaluation of newly integrated bivalirudin titration protocol in patients with mechanical circulatory support
M Mitchell, D Sullinger, D Dyer… - Annals of …, 2024 - journals.sagepub.com
Background: Patients with cardiogenic shock or end-stage heart failure can be maintained
on mechanical circulatory support (MCS) devices. Once a patient undergoes placement of a …
on mechanical circulatory support (MCS) devices. Once a patient undergoes placement of a …
Direct thrombin inhibitor resistance and possible mechanisms
M Cardinale, M Ha, MH Liu… - Hospital Pharmacy, 2016 - journals.sagepub.com
Objective To report 3 cases in which doses of bivalirudin higher than commonly used in
clinical practice were required in order to achieve therapeutic anticoagulation as monitored …
clinical practice were required in order to achieve therapeutic anticoagulation as monitored …
[HTML][HTML] Considerations for analgosedation and antithrombotic management during extracorporeal life support
PK Burcham, AJ Rozycki, EE Abel - Annals of Translational …, 2017 - ncbi.nlm.nih.gov
Despite the immense growth in extracorporeal life support (ECLS) technology and
experience, opportunity remains to better characterize the pharmacotherapeutic …
experience, opportunity remains to better characterize the pharmacotherapeutic …
Intravenous warfarin and heparin-induced thrombocytopenia: making the diagnosis, management, modern monitoring, and multidisciplinary care
CF Burger, JJ Schlesinger - Annals of Pharmacotherapy, 2014 - journals.sagepub.com
Objective: To describe the diagnosis, management, and monitoring of a patient with heparin-
induced thrombocytopenia (HIT) with thrombosis and simultaneous bleeding risk treated …
induced thrombocytopenia (HIT) with thrombosis and simultaneous bleeding risk treated …
[HTML][HTML] Harms Due to Anticoagulants
SJ Shoemaker-Hunt, B Wyant - … Safer III: A Critical Analysis of …, 2020 - ncbi.nlm.nih.gov
Anticoagulants are a critical therapy in the prevention and treatment of various types of
thromboembolic disorders. Key indications for anticoagulants include the prevention of …
thromboembolic disorders. Key indications for anticoagulants include the prevention of …
Risk Factors and Outcomes Associated with Prolonged Subtherapeutic Anticoagulation with Bivalirudin: A Retrospective Cohort Study
Background Bivalirudin, a direct thrombin inhibitor, is a treatment option for the management
of heparin‐induced thrombocytopenia (HIT) and other coagulation disorders. To date, no …
of heparin‐induced thrombocytopenia (HIT) and other coagulation disorders. To date, no …
Practical Pharmacokinetics and Pharmacodynamics
AT Gerlach, L Saliba - Principles of Adult Surgical Critical Care, 2016 - Springer
The physiological responses to surgery, critical illness, and subsequent resuscitation can
alter both pharmacokinetics (PK) and pharmacodynamics (PD)[1]. As a result of these …
alter both pharmacokinetics (PK) and pharmacodynamics (PD)[1]. As a result of these …