Mesenchymal stem cell-derived exosome mitigates colitis via the modulation of the gut metagenomics–metabolomics–farnesoid X receptor axis

DKW Ocansey, Z Zhang, X Xu, L Liu, S Amoah… - Biomaterials …, 2022 - pubs.rsc.org
Inflammatory bowel disease (IBD) is associated with chronic gut immune dysregulation and
altered microbiome and metabolite composition. Bile acids and their receptors such as the …

[HTML][HTML] Thyroid Eye Disease and Glaucoma: A Cross-Sectional Study Comparing Clinical Characteristics and Disease Severity

LA Ghenciu, AM Șișu, ER Stoicescu, AI Dănilă… - Medicina, 2024 - mdpi.com
Background and Objectives: This study investigates the relationship between thyroid eye
disease (TED) and open-angle glaucoma (OAG), focusing on disease severity and clinical …

Therapeutic role of erythropoietin in methanol induced optic neuropathy: a systematic review

N Feizi, M Mohamadzadeh-Nabiei, H Vahedi… - DARU Journal of …, 2024 - Springer
Purpose Despite various therapeutic attempts, an approved treatment for Methanol-induced
optic neuropathy (MION), a sight-threatening disorder, is still lacking. Erythropoietin known …

NeuroBehcet's-related intracranial hypertension without cerebral venous thrombosis: case report and review of literature

JM Shah, W Fong, DA De Silva - BMC neurology, 2024 - Springer
Background We present a rare case of NeuroBehcet's-related intracranial hypertension
without cerebral venous thrombosis (NBrIHwCVT), occurring as the first presentation of …

Epidemiology and clinical presentation of glaucoma in a referral facility in Ghana: Any lessons for public health intervention?

S Kyei, PA Obeng, MA Kwarteng, F Assiamah - Plos one, 2021 - journals.plos.org
The purpose of this study was to evaluate the epidemiological and clinical profile of patients
living with glaucoma and receiving care in a tertiary eye center in Ghana. This was a …

Multi-modal retinal imaging for investigating neurovascular health

S Gibbon, C Hamid, A Threlfall, C Ritchie, B Dhillon… - Eye, 2024 - nature.com
The PREVENT Dementia study [1] is capturing 2D images of the retina using four modalities
(ultra-widefield, colour fundus photography, scanning laser ophthalmoscopy, and optical …

[HTML][HTML] Racial Differences in Diagnostic Accuracy of Retinal Nerve Fiber Layer Thickness in Primary Open-Angle Glaucoma

MT KhalafAllah, LM Zangwill, J Proudfoot… - American Journal of …, 2024 - Elsevier
PURPOSE To evaluate the diagnostic accuracy of retinal nerve fiber layer thickness
(RNFLT) by spectral-domain optical coherence tomography (OCT) in primary open-angle …

[HTML][HTML] PallorMetrics: Software for Automatically Quantifying Optic Disc Pallor in Fundus Photographs, and Associations With Peripapillary RNFL Thickness

S Gibbon, G Muniz-Terrera, FSL Yii… - … Vision Science & …, 2024 - iovs.arvojournals.org
Purpose: We sough to develop an automatic method of quantifying optic disc pallor in
fundus photographs and determine associations with peripapillary retinal nerve fiber layer …

A method for quantifying sectoral optic disc pallor in fundus photographs and its association with peripapillary RNFL thickness

S Gibbon, G Muniz-Terrera, FSL Yii, C Hamid… - arXiv preprint arXiv …, 2023 - arxiv.org
Purpose: To develop an automatic method of quantifying optic disc pallor in fundus
photographs and determine associations with peripapillary retinal nerve fibre layer (pRNFL) …

Five-year changes in retinal nerve fibre layer thickness in the adult population: a population-based cohort study

H Hashemi, M Khabazkhoob, S Heydarian… - Clinical and …, 2024 - Taylor & Francis
Clinical relevance Distinguishing between the pathological thinning of the retinal nerve fibre
layer (RNFL) and age-related reduction requires a comprehensive understanding of the …