Posterior cortical atrophy (PCA) is a neurodegenerative syndrome that is characterised by
progressive decline in visuospatial, visuoperceptual, literacy, and praxic skills. The …

Variant syndromes of Alzheimer disease (AD), led by deficits that extend beyond memory
dysfunction, are of considerable clinical and neurobiological importance. Such syndromes …

Introduction A classification framework for posterior cortical atrophy (PCA) is proposed to
improve the uniformity of definition of the syndrome in a variety of research settings. Methods …

In the past 8 years, both the International Working Group (IWG) and the US National Institute
on Aging–Alzheimer's Association have contributed criteria for the diagnosis of Alzheimer's …

The factors driving clinical heterogeneity in Alzheimer's disease are not well understood.
This study assessed the relationship between amyloid deposition, glucose metabolism and …

Neuroketotherapeutics represent a class of bioenergetic medicine therapies that feature the
induction of ketosis. These therapies include medium-chain triglyceride supplements …

Patients with Alzheimer's disease (AD), the most prevalent neurodegenerative dementia, are
usually elderly; however,∼ 4–5% develop early-onset AD (EOAD) with onset before age 65 …

Alzheimer's disease (AD) differentially and specifically affects brain regions and neuronal
cell types in a predictable pattern. Damage to the brain appears to spread and worsens with …

Background Corticobasal degeneration (CBD) is a complex neurodegenerative disorder.
Accurate diagnosis is increasingly important, with the advent of clinical trials of drugs aimed …

The clinical spectrum of Alzheimer's disease (AD) extends well beyond the classic amnestic–
predominant syndrome. The previous studies have suggested differential neurofibrillary …