Mesenchymal stromal cells (MSCs) are multipotent cells, which can give rise to several cell
types including osteoblasts, adipocytes, and chondroblasts. These cells can be found in a …

Progress in the understanding of the biology of perinatal tissues has contributed to the
breakthrough revelation of the therapeutic effects of perinatal derivatives (PnD), namely birth …

Mesenchymal stromal cells (MSCs) are multipotent cells, immunomodulatory stem cells that
are currently used for regenerative medicine and treatment of a number of inflammatory …

Background: Epithelial-to-mesenchymal transition (EMT) has a central role in cancer
progression and metastatic dissemination and may be induced by local inflammation. We …

Stem cell-based therapy has become an attractive and promising approach for the treatment
of severe injuries or thus-far incurable diseases. However, the use of stem cells is often …

Mesenchymal stem cells (MSCs) display pleiotropic functions, which include secretion of
soluble factors with immunosuppressive activity implicated in cancer progression. We …

Acute-on-chronic liver failure (ACLF) is a severe disease with a high mortality. Macrophage-
related inflammation plays a crucial role in ACLF development. Mesenchymal stem cells …

Notch and Wnt signaling are highly conserved intercellular communication pathways
involved in developmental processes, such as hematopoiesis. Even though data from …

Somatic stem cells have been obtained from solid organs and tissues, including the bone
marrow, placenta, corneal stroma, periosteum, adipose tissue, dental pulp and skeletal …

Mesenchymal stromal cells (MSCs) are adult, multipotent cells of mesodermal origin
representing the progenitors of all stromal tissues. MSCs possess significant and broad …