The miRNA: a small but powerful RNA for COVID-19
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is a severe and rapidly evolving epidemic. Now …
syndrome coronavirus 2 (SARS-CoV-2) is a severe and rapidly evolving epidemic. Now …
The many faces of estrogen signaling
P Vrtačnik, B Ostanek, S Mencej-Bedrač, J Marc - Biochemia medica, 2014 - hrcak.srce.hr
Sažetak Estrogens have long been known as important regulators of the female
reproductive functions; however, our understanding of the role estrogens play in the human …
reproductive functions; however, our understanding of the role estrogens play in the human …
MicroRNAs in ovarian follicular atresia and granulosa cell apoptosis
J Zhang, Y Xu, H Liu, Z Pan - Reproductive Biology and Endocrinology, 2019 - Springer
MicroRNAs (miRNAs) are short, noncoding RNAs that posttranscriptionally regulate gene
expression. In the past decade, studies on miRNAs in ovaries have revealed the key roles of …
expression. In the past decade, studies on miRNAs in ovaries have revealed the key roles of …
miR-190 suppresses breast cancer metastasis by regulation of TGF-β-induced epithelial–mesenchymal transition
Y Yu, W Luo, ZJ Yang, JR Chi, YR Li, Y Ding, J Ge… - Molecular cancer, 2018 - Springer
Background Breast cancer is the most common cancer among women worldwide and
metastasis is the leading cause of death among patients with breast cancer. The …
metastasis is the leading cause of death among patients with breast cancer. The …
LNMICC promotes nodal metastasis of cervical cancer by reprogramming fatty acid metabolism
C Shang, W Wang, Y Liao, Y Chen, T Liu, Q Du… - Cancer research, 2018 - AACR
Cancer spread to lymph nodes predicts poor survival but underlying mechanisms remain
little understood. In this study, we show that overexpression of the long noncoding RNA …
little understood. In this study, we show that overexpression of the long noncoding RNA …
Pathophysiology 1. Mechanisms of thrombosis in cancer patients
A Falanga, F Schieppati, L Russo - Thrombosis and hemostasis in cancer, 2019 - Springer
Thrombosis is a major cause of morbidity and mortality in cancer patients. The pathogenesis
of blood coagulation activation in oncological patients is complex and involves both clinical …
of blood coagulation activation in oncological patients is complex and involves both clinical …
Identification of potential microRNA diagnostic panels and uncovering regulatory mechanisms in breast cancer pathogenesis
Z Sharifi, M Talkhabi, S Taleahmad - Scientific Reports, 2022 - nature.com
Early diagnosis of breast cancer (BC), as the most common cancer among women,
increases the survival rate and effectiveness of treatment. MicroRNAs (miRNAs) control …
increases the survival rate and effectiveness of treatment. MicroRNAs (miRNAs) control …
miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets
CM Klinge - Molecular and cellular endocrinology, 2015 - Elsevier
Abstract MicroRNAs (miRNAs) are short (22 nucleotides), single-stranded, non-coding
RNAs that form complimentary base-pairs with the 3′ untranslated region of target mRNAs …
RNAs that form complimentary base-pairs with the 3′ untranslated region of target mRNAs …
Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer
CF Jiang, ZM Shi, DM Li, YC Qian, Y Ren, XM Bai… - Molecular cancer, 2018 - Springer
Background Estrogen plays a critical role in breast cancer (BC) progression through
estrogen receptor (ER)-mediated gene regulation. Emerging studies suggest that the …
estrogen receptor (ER)-mediated gene regulation. Emerging studies suggest that the …
Hijacking and rewiring of host CircRNA/miRNA/mRNA competitive endogenous RNA (ceRNA) regulatory networks by oncoviruses during development of viral …
A significant portion of human cancers are caused by oncoviruses (12%–25%). Oncoviruses
employ various strategies to promote their replication and induce tumourigenesis in host …
employ various strategies to promote their replication and induce tumourigenesis in host …