Microglia are brain phagocytes that participate in brain homeostasis and continuously
survey their environment for dysfunction, injury, and disease. As the first responders …

Determining regions of altered brain physiology after diffuse brain injury is challenging.
Microglia, brain immune cells with ramified and dynamically moving processes, constantly …

Microglial immunosurveillance of the brain parenchyma to detect local perturbations in
homeostasis, in all species, results in the adoption of a spectrum of morphological changes …

Signaling by insulin-like growth factor-1 (IGF-1) is essential for the development of the
central nervous system (CNS) and regulates neuronal survival and myelination in the adult …

Water plastic pollution is a serious problem affecting sealife, marine habitats, and the food
chain. Artificial intelligence-enabled coherent imaging has recently shown exciting …

Background Ischemic stroke is an acquired brain injury with gender-dependent outcomes. A
persistent obstacle in understanding the sex-specific neuroinflammatory contributions to …

We previously showed the anti-inflammatory effects of kynurenic acid (KYNA) and its brain-
penetrable analog N-(2-(dimethylamino) ethyl)-3-(morpholinomethyl)-4-hydroxyquinoline-2 …

Microglia, the innate immune cells of the CNS parenchyma, serve as the first line of defense
in a myriad of neurodevelopmental, neurodegenerative, and neuroinflammatory conditions …

Adolescent exposure to chronic stress, a risk factor for mood disorders in adulthood,
sensitizes the neuroinflammatory response to a subsequent immune challenge. We …

Background and aim Cordyceps militaris (CM) and Armillaria mellea (AM) are medicinal
mushrooms with potential applications in the treatment of mood disorders, including …