Over the past decade, mRNA modifications have emerged as important regulators of gene
expression control in cells. Fueled in large part by the development of tools for detecting …

Abstract N 6-Methyladenosine (m6A), the most abundant internal modification associated
with eukaryotic mRNAs, has emerged as a dynamic regulatory mechanism controlling the …

Double-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired,
may lead to genome instability or cell death. Here, we report that, in response to DSBs, the …

N 6-Methyladenosine (m 6 A), the most prevalent internal modification associated with
eukaryotic mRNAs, influences many steps of mRNA metabolism, including splicing, export …

RNAs fold into 3D structures that range from simple helical elements to complex tertiary
structures and quaternary ribonucleoprotein assemblies. The functions of many regulatory …

With advanced technologies to map RNA modifications, our understanding of them has
been revolutionized, and they are seen to be far more widespread and important than …

This review aims at juxtaposing common versus distinct structural and functional strategies
that are applied by aptamers, riboswitches, and ribozymes/DNAzymes. Focusing on recently …

Many cellular mRNAs contain the modified base m6A, and recent studies have suggested
that various stimuli can lead to changes in m6A. The most common method to map m6A and …

The transport of mRNAs to distal subcellular compartments is an important component of
spatial gene expression control in neurons. However, the mechanisms that control mRNA …

Innate lymphoid cells (ILCs) can quickly switch from a quiescent state to an active state and
rapidly produce effector molecules that provide critical early immune protection. How the …