Esophageal cancer (EC) is a disease often marked by aggressive growth and poor
prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant …

Chemokines, which have chemotactic abilities, are comprised of a family of small cytokines
with 8-10 kilodaltons. Chemokines work in immune cells by trafficking and regulating cell …

Chemokines and chemokine receptors regulate multiple processes such morphogenesis,
angiogenesis and immune responses. Among the chemokine receptors, CXCR4 stands out …

In recent years, molecular imaging addressing the CXC motif chemokine receptor 4
(CXCR4) has increasingly been used in various clinical settings. Here, we aimed to assess …

CXCL12 is a CXC chemokine that traditionally has been classified as a homeostatic
chemokine. It contributes to physiological processes such as embryogenesis, hematopoiesis …

Constitutive receptor activity/inverse agonism and functional selectivity/biased agonism are
2 concepts in contemporary pharmacology that have major implications for the use of drugs …

Chemokine networks regulate a variety of cellular, physiological, and immune processes.
These normal functions can become appropriated by cancer cells to facilitate a more …

Chemokines are small secretory chemotactic cytokines that control the directed migration of
immune cells. Chemokines are involved in both anti-and pro-tumorigenic immune …

Background Quercetin, nature's most common flavonoid, possesses anticarcinogenic
properties against various forms of cancer. The aim of this study was to investigate the effect …

Simple Summary Breast cancer remains the most common malignancy in women. In this
review, we explore the role of the CXCL12/CXCR4 pathway in breast cancer. We show that …