Abstract The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows
a significant degree of variation within populations. IgG glycome composition is influenced …

The effective treatment of autoimmune disorders can greatly benefit from disease-specific
biomarkers that are functionally involved in immune system regulation and can be collected …

The diversity of glycans expression within a cell or an organism is enormous and the amount
of relevant biological information that each glycan structure encodes is far from being …

It is speculated that immunoglobulin G (IgG) plays a regulatory role in allergic reactions. The
glycans on the Fc region are known to affect IgG effector functions, thereby possibly having a …

A variety of biological processes are regulated by posttranslational modifications.
Posttranslational modifications including phosphorylation, ubiquitination, glycosylation, and …

Abstract Objective Thyroglobulin antibody (TgAb) is an important autoantibody in thyroid
diseases, which is a glycoprotein, predominantly of IgG class. Glycosylation of the IgG-Fc …

The human total serum N‐glycome (TSNG) is the representation of the serum glycoproteins
N‐glycosylation. The study of N‐glycosylation in clinical biochemistry laboratories is …

We report the structure of the Fc fragment of rabbit IgG at 1.95 Å (1 Å= 0.1 nm) resolution.
Rabbit IgG was the molecule for which Porter established the four-chain, Υ-shaped structure …

Early studies of the humoral immune response revealed an apparent paradox: an infinite
diversity of antibody specificities encoded within a finite genome. In consequence antibodies …

Abstract Changes in immunoglobulin G (IgG) glycosylation pattern have been observed in a
vast array of auto-and alloimmune, infectious, cardiometabolic, malignant, and other …