The biopharmaceutical market has experienced a tremendous growth in the last years.
However, this growth should be balanced considering the difficulty in bioproduct …

The biopharmaceutical industry is still running in batch mode, mostly because it is highly
regulated. In the past, sensors were not readily available and in‐process control was mainly …

The biopharmaceutical industries are continuously faced with the pressure to reduce the
development costs and accelerate development time scales. The traditional approach of …

In this study, we demonstrated the first, to our knowledge, integrated continuous bioprocess
(ICB) designed for the production of acid‐sensitive monoclonal antibodies, prone to …

Multi-column periodic counter-current chromatography (PCC) has attracted wide attention
for the primary capture for the purpose of achieving continuous biomanufacturing …

The methodology for production of biologics is going through a paradigm shift from batch‐
wise operation to continuous production. Lot of efforts are focused on integration …

Traditional chromatographic purification steps consist of long loading steps at a constant
residence time, especially during early stages of the downstream process. The breakthrough …

Chromatographic separation processes are described by nonlinear partial differential and
algebraic equations, which may result in high computational cost, hindering further online …

Monoclonal antibody (mAb) is a widely used therapeutic modality that is being used for
treatment of chronic diseases like cancer, psoriasis, and other auto immune diseases. The …

The present work aims to accelerate sports development in China and promote
technological innovation in the artificial intelligence (AI) field. After analyzing the application …