Amyloid proteins, which are known as unstructured protein, are able to self-aggregate to
form amyloid fibrils, which are related to pathogenesis of various diseases ranging from …

Monitoring early-stage β-amyloid (Aβ) dimerization is a formidable challenge for
understanding neurological diseases. We compared β-sheet formation and histidine site …

Controlling protein misfolding and accumulation in neurodegeneration is a challenge in
chemical neuroscience. The application of appropriate electric fields (EFs) can be a …

Hypoxanthine is the doping component in anhydrous guanine β (AG β) biominerals. In this
work, hypoxanthine was doped into all the reported guanine phases by solution methods …

Hundreds of millions of people around the world have been affected by Type 2 diabetes
(T2D) which is a metabolic disorder. Clinical research has revealed T2D as a possible risk …

Histidine behaviors (including tautomeric and protonation behaviors, and integration on ε, δ,
or p states) have been linked to protein folding and misfolding. However, the histidine …

Abstract Characterization of the conformational alterations involved in monomer misfolding
is essential for elucidating the molecular basis of the initial stage of protein accumulation …

Intermolecular interactions between aromatic amino acids were investigated by ultraviolet
photodissociation spectroscopy of hydrogen-bonded protonated clusters of histidine (His) …