Non-ribosomal peptide synthetases (NRPSs) are attractive targets for biosynthetic pathway
engineering due to their modular architecture and the therapeutic relevance of their …

Polyketides are a diverse class of compounds with significant interest in the pharmaceutical
industry. They are synthesized by polyketide synthases (PKSs), which consist of large …

Owing to their role in activating enzymes essential for bacterial viability and pathogenicity,
phosphopantetheinyl transferases represent novel and attractive drug targets. In this work …

The oxoglutarate dehydrogenase complex (OGDHc) participates in the tricarboxylic acid
cycle and, in a multi-step reaction, decarboxylates α-ketoglutarate, transfers succinyl to CoA …

Cell-free systems display tremendous potential for biotechnological applications,
complementing in vitro reconstituted enzymatic processes and traditional expression …