Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics

L Migliore, F Coppedè - Nature Reviews Neurology, 2022 - nature.com
With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

Sustainable and efficient technologies for removal and recovery of toxic and valuable metals from wastewater: Recent progress, challenges, and future perspectives

A Abidli, Y Huang, ZB Rejeb, A Zaoui, CB Park - Chemosphere, 2022 - Elsevier
Due to their numerous effects on human health and the natural environment, water
contamination with heavy metals and metalloids, caused by their extensive use in various …

Diet in the prevention of Alzheimer's disease: current knowledge and future research requirements

O Stefaniak, M Dobrzyńska, S Drzymała-Czyż… - Nutrients, 2022 - mdpi.com
Alzheimer's disease is a progressive brain disease that is becoming a major health problem
in today's world due to the aging population. Despite it being widely known that diet has a …

Combination drug therapy for the management of Alzheimer's disease

MT Kabir, MS Uddin, AA Mamun, P Jeandet… - International Journal of …, 2020 - mdpi.com
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Even though the
number of AD patients is rapidly growing, there is no effective treatment for this …

Effects of in vivo conditions on amyloid aggregation

MC Owen, D Gnutt, M Gao, SKTS Wärmländer… - Chemical Society …, 2019 - pubs.rsc.org
One of the grand challenges of biophysical chemistry is to understand the principles that
govern protein misfolding and aggregation, which is a highly complex process that is …

Molecular mechanisms of metal toxicity in the pathogenesis of Alzheimer's disease

MT Kabir, MS Uddin, S Zaman, Y Begum… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is the most common form of dementia, which is progressively
affecting elderly people. The dyshomeostasis of biometals and accumulation of toxic metals …

Metal-organic frameworks: A promising option for the diagnosis and treatment of Alzheimer's disease

S Tajahmadi, H Molavi, F Ahmadijokani… - Journal of Controlled …, 2023 - Elsevier
Beta-amyloid (Aβ) peptide is one of the main characteristic biomarkers of Alzheimer's
disease (AD). Previous clinical investigations have proposed that unusual concentrations of …

Zebrafish as a potential model for neurodegenerative diseases: a focus on toxic metals implications

E Paduraru, D Iacob, V Rarinca, G Plavan… - International Journal of …, 2023 - mdpi.com
In the last century, industrial activities increased and caused multiple health problems for
humans and animals. At this moment, heavy metals are considered the most harmful …

Multi-target drug candidates for multifactorial Alzheimer's disease: AChE and NMDAR as molecular targets

MS Uddin, A Al Mamun, MT Kabir, GM Ashraf… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is one of the most common forms of dementia among elder
people, which is a progressive neurodegenerative disease that results from a chronic loss of …

[HTML][HTML] Simultaneous removal of copper and zinc ions by Chitosan/Hydroxyapatite/nano-Magnetite composite

A Pooladi, R Bazargan-Lari - Journal of Materials Research and …, 2020 - Elsevier
In this study, we assessed the simultaneous removal of Cu (II) and Zn (II) from aqueous
solutions, using Chitosan/Hydroxyapatite/nano-Magnetite (Fe 3 O 4) composite as an …