Copper is one of the most abundant basic transition metals in the human body. It takes part
in oxygen metabolism, collagen synthesis, and skin pigmentation, maintaining the integrity …

With the increasing life expectancy in developed countries, the incidence of Alzheimer's
disease (AD) and thus its socioeconomic impact are growing. Increasing knowledge over …

A sensitive and accurate imaging technique capable of tracking the disease progression of
Alzheimer's Disease (AD) driven amnestic dementia would be beneficial. A currently …

Formation of senile plaques composed of amyloid β peptide, a pathological hallmark of
Alzheimer disease, in human brains precedes disease onset by many years. Noninvasive …

Purpose A method named DECOMPOSE-QSM is developed to decompose bulk
susceptibility measured with QSM into sub-voxel paramagnetic and diamagnetic …

The metal ions of iron, copper, and zinc have long been associated with the aggregation of β-
amyloid (Aβ) plaques in Alzheimer's disease; an interaction that has been suggested to …

Although epidemiological studies and retrospective autopsy data provide evidence that a
later cognitive decline may occur after severe traumatic brain injury, the relationship …

Recent advances in understanding the molecular mechanisms underlying various paths
toward the pathogenesis of Alzheimer's disease (AD) has begun to provide new insight for …

Alzheimer's disease (AD) is the most common cause of dementia worldwide. As advancing
age is the greatest risk factor for developing AD, the number of those afflicted is expected to …

Amyloid plaques are one of the pathological hallmarks of Alzheimer's disease (AD). The
visualization of amyloid plaques in the brain is important to monitor AD progression and to …