Keeping the integrity and transparency of the cornea is the most important issue to ensure
normal vision. There are more than 10 million patients going blind due to the cornea …

Limbal niche cells located in the limbal Palisades of Vogt are mesenchymal stem cells that
reside next to limbal basal epithelial cells. Limbal niche cells are progenitors that express …

Background Limbal stem cell transplantation (LSCT) is the definitive treatment for total limbal
stem cell deficiency (LSCD). This study evaluates the anatomical and visual outcomes of a …

Purpose: Limbal epithelial stem cells (LSCs), located in the basal layer of the corneal
epithelium in the corneal limbus, are vital for maintaining the corneal epithelium. LSCs have …

To expand multi-potent progenitors from human trabecular meshwork (TM), we have created
a new optimized method on two-dimensional (2D) followed by three–dimensional (3D) …

This study aimed to determine the effect of interleukin-13 (IL13) on the stemness,
differentiation, proliferation, clonogenicity, and morphology of cultured limbal epithelial cells …

Limbal stem cell deficiency (LSCD) is a clinically treatment-challenging eye disease caused
by damage to limbal stem cells (LSCs). Currently, the international consensus classifies …

Simple Summary Contact lens (CL)-induced limbal stem cell deficiency (LSCD) is not well-
known and is one of the lesser-understood causes of LSCD. With increasing contact lens …

Shipping time and shipping delays might affect the quality of the stem cells based
engineered “organs.” In our laboratory, we have developed a limbal stem cell deficient …

Purpose: Although stem cell activity represents a crucial feature in corneal and ocular
surface homeostasis, other cells populating this region and the neighboring zones might …