Measuring biological aging in humans: A quest
L Ferrucci, M Gonzalez‐Freire, E Fabbri… - Aging cell, 2020 - Wiley Online Library
The global population of individuals over the age of 65 is growing at an unprecedented rate
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …
and is expected to reach 1.6 billion by 2050. Most older individuals are affected by multiple …
An update on the biology and management of dyskeratosis congenita and related telomere biology disorders
MR Niewisch, SA Savage - Expert review of hematology, 2019 - Taylor & Francis
ABSTRACT Introduction: Telomere biology disorders (TBDs) encompass a group of
illnesses caused by germline mutations in genes regulating telomere maintenance, resulting …
illnesses caused by germline mutations in genes regulating telomere maintenance, resulting …
RTEL1 influences the abundance and localization of TERRA RNA
F Ghisays, A Garzia, H Wang… - Nature …, 2021 - nature.com
Abstract Telomere repeat containing RNAs (TERRAs) are a family of long non-coding RNAs
transcribed from the subtelomeric regions of eukaryotic chromosomes. TERRA transcripts …
transcribed from the subtelomeric regions of eukaryotic chromosomes. TERRA transcripts …
Multisystemic manifestations in rare diseases: the experience of dyskeratosis congenita
M Callea, D Martinelli, F Cammarata-Scalisi… - Genes, 2022 - mdpi.com
Dyskeratosis congenital (DC) is the first genetic syndrome described among
telomeropathies. Its classical phenotype is characterized by the mucocutaneous triad of …
telomeropathies. Its classical phenotype is characterized by the mucocutaneous triad of …
Is hull cleaning wastewater a potential source of developmental toxicity on coastal non-target organisms?
Y Choi, M Kim, CP Hong, JH Kang, JH Jung - Aquatic Toxicology, 2020 - Elsevier
Chemical contaminants can be discharged by vessel hull cleaning processes, such as
scraping, jet spraying, and painting, all of which produce readily transportable contaminants …
scraping, jet spraying, and painting, all of which produce readily transportable contaminants …
Aspectos clínicos, etiológicos y terapéuticos de la disqueratosis congénita
R Perona, L Sastre, M Callea… - Revista Peruana de …, 2020 - revistas.unheval.edu.pe
La disqueratosis congénita corresponde la primera entidad genética descrita entre las
telomeropatías, cuya forma clásica se caracteriza por presentar la tríada mucocutánea de …
telomeropatías, cuya forma clásica se caracteriza por presentar la tríada mucocutánea de …
[PDF][PDF] A novelDKC1gene mutation c. 1177 A> T (p. I393F) in a case of dyskeratosis congenita with severe telomere shortening
P Mohanty, P Jadhav, C Shanmukhaiah, S Kumar… - Int J …, 2019 - researchgate.net
Dyskeratosis congenita (DC) is an inherited, progressive bone marrow failure (BMF) and
cancer predisposition syndrome with a prevalence of one in 1,000,000 people. The clinical …
cancer predisposition syndrome with a prevalence of one in 1,000,000 people. The clinical …
Alternative Splicing Regulation of Human Telomerase Reverse Transcriptase (TERT): Cancer Therapeutic Implications, Discovery of Novel TERT Isoforms, and Impact …
J Kim - 2023 - deepblue.lib.umich.edu
Aging is associated with an elevated cancer risk due to the cumulative genetic mutations,
cellular damage, and loss of immune cell function. Telomeres, the protective caps at the …
cellular damage, and loss of immune cell function. Telomeres, the protective caps at the …
[PDF][PDF] Multisystemic Manifestations in Rare Diseases: The Experience of Dyskeratosis Congenita. Genes 2022, 13, 496
M Callea, D Martinelli, FC Scalisi, C Grimaldi, H Jilani… - 2022 - core.ac.uk
Dyskeratosis congenital (DC) is the first genetic syndrome described among
telomeropathies. Its classical phenotype is characterized by the mucocutaneous triad of …
telomeropathies. Its classical phenotype is characterized by the mucocutaneous triad of …