In recent years, transdermal preparations have emerged as one of the most promising
modes of administration. In particular, dissolving microneedles have attracted extensive …

Articular cartilage is a remarkable tissue whose sophisticated composition and architecture
allow it to withstand complex stresses within the joint. Once injured, cartilage lacks the …

Microneedles offer a convenient transdermal delivery route with potential for long term
sustained release of drugs. However current microneedle technologies may not have the …

Osteoarthritis (OA) is a common chronic inflammatory disease in the joints. It is one of the
leading causes of disability with increasing morbidity, which has become one of the serious …

Suture materials based on poly (lactic acid)(PLA) were developed by means of two different
methods: extrusion and electrospinning, which were followed by a supercritical CO 2 …

Periodontal disease is a chronic inflammation of gum and tissues that surround and support
the teeth. Nonsteroidal anti-inflammatory drugs (NSAIDs) can be used in the treatment of …

Stable hydrogels with tunable rheological properties were prepared by adding Ca2+ ions to
aqueous dispersions of 2, 2, 6, 6-tetramethylpiperidine 1-oxyl (TEMPO)-oxidized and ultra …

The aim was to assess the suitability of three nano-based transdermal drug delivery systems
containing ibuprofen: a nano-emulsion, a nano-emulgel, and a colloidal suspension with …

In this study, hydrogels containing ibuprofen-loaded solid lipid nanoparticles (IBU-loaded
SLNs) were developed to enhance the skin penetration of ibuprofen and for the local …

The incorporation of drugs and bioactive compounds in the natural rubber latex (NRL) matrix
has been an alternative for the development of transdermal release membranes. Ibuprofen …