Viruses are nanoscale entities containing a nucleic acid genome encased in a protein shell
called a capsid and in some cases are surrounded by a lipid bilayer membrane. This review …

Most viruses use a hollow protein shell, the capsid, to enclose the viral genome. Virus
capsids are large, symmetric oligomers made of many copies of one or a few types of protein …

Molecular simulations are performed to study the self-assembly of particles with discrete,
attractive interaction sites−“patches”− at prescribed locations on the particle surface. Chains …

We develop a class of models with which we simulate the assembly of particles into T1
capsidlike objects using Newtonian dynamics. By simulating assembly for many different …

The capsids of most spherical viruses are icosahedral, an arrangement of multiples of 60
subunits. Though it is a salient point in the life cycle of any virus, the physical chemistry of …

Viruses play a role in a significant portion of human diseases, as well as those of other
animals, plants, and bacteria. This chapter focuses on the use of theoretical and …

The assembly of virus capsids or other spherical polymers—empty, closed structures
composed of hundreds of protein subunits—is poorly understood. Assembly of a closed …

In this perspective article, we focus on recent developments in the theory of charge effects in
biological DNA-related systems. The electrostatic effects on different levels of DNA …

A fundamental step in the replication of a viral particle is the self-assembly of its rigid shell
(capsid) from its constituent proteins. Capsids play a vital role in genome replication and …

Self-assembly is widely used by biological systems to build functional nanostructures, such
as the protein capsids of RNA viruses. But because assembly is a collective phenomenon …