Ultra-long-acting delivery platforms for HIV pre-exposure prophylaxis (PrEP) may increase
adherence and maximize public health benefit. We report on an injectable, biodegradable …

In-situ forming implants (ISFIs) represent a simple, tunable, and biodegradable polymer-
based platform for long-acting drug delivery. However, drugs with different physicochemical …

Despite the unique advantages of injectable, long-acting in situ forming implant formulations
based on poly (lactide-co-glycolide)(PLGA) and N-Methyl-2-Pyrrolidone (NMP), only six …

The aim of the study was to design injectable long-acting poly (lactide-co-glycolide)(PLGA)-
based in situ gel implants (ISGI) loaded with the anti-diabetic alogliptin. Providing sustained …

Introduction Intramuscular (IM) injections deliver a plethora of drugs. The majority of IM-
related literature details dissolution and/or pharmacokinetic (PK) studies, using methods …

Only condoms are proven to protect against both HIV and unplanned pregnancy, however,
poor user acceptability and lack of partner cooperation impede effectiveness. We developed …

Electromagnetic fields can penetrate aqueous media in a homogeneous and instantaneous
way, without physical contact, independently of its temperature, pressure, agitation degree …

Women account for 53% of people living with HIV worldwide and women and girls in sub-
Saharan Africa account for 60% of all new HIV infections. Adherence to daily oral regimens …

More than 50% of approved drugs on the market contain poorly water-soluble APIs, which
typically are associated with poor bioavailability, suboptimal drug delivery, ineffective drug …