Gut-associated lymphoid tissues (GALT) are the key antigen sampling and adaptive immune
inductive sites within the intestinal wall. Human GALT includes the multi-follicular Peyer's …

Microsatellite unstable (MSI) colorectal cancers (CRCs) are due to DNA mismatch repair
(MMR) deficiency and occurs in15% of non-metastatic diseases and 5% in the metastatic …

Many tumour antigens that do not arise from cancer cell-specific mutations are targets of
humoral and cellular immunity despite their expression on non-malignant cells. Thus, in …

Simple Summary Defects in a DNA repair pathway called mismatch repair (MMR) can lead
to cancer, including colorectal cancer (CRC). The detection of mismatch repair deficiency …

Background Tertiary lymphoid structures (TLSs) are immune aggregates in peripheral
tissues that may support adaptive immune responses. Their presence has been associated …

Tertiary lymphoid structures (TLSs), which consist of B cells, T cells, follicular dendritic cells
and high endothelial venules, have recently been found to be associated with effective …

Gut-associated lymphoid tissues (GALTs) comprise key intestinal immune inductive sites,
including the Peyer's patches of the small intestine and different types of isolated lymphoid …

Simple Summary Colorectal cancer is the second leading cause of cancer-related death
worldwide. The immune system plays a key role in controlling tumour onset and …

Background Accurate estimation of the long-term risk of recurrence in patients with non-
metastatic colorectal cancer (CRC) is crucial for clinical management. Histology-based deep …

Simple Summary At present, research on tertiary lymphoid structures (TLSs) in
hepatocellular carcinoma (HCC) has been limited to the prognostic impact. Our manuscript …