American Association of Clinical Endocrinology clinical practice guideline for the diagnosis and management of nonalcoholic fatty liver disease in primary care and …

K Cusi, S Isaacs, D Barb, R Basu, S Caprio… - Endocrine Practice, 2022 - Elsevier
Objective To provide evidence-based recommendations regarding the diagnosis and
management of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis …

Non‐alcoholic fatty liver disease and type 2 diabetes: An update

CH Lee, DTW Lui, KSL Lam - Journal of Diabetes Investigation, 2022 - Wiley Online Library
The global prevalence of non‐alcoholic fatty liver disease (NAFLD) is rising, along with the
epidemic of diabesity. NAFLD is present in> 70% of individuals with type 2 diabetes …

AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease

ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

Semaglutide 2· 4 mg once weekly in patients with non-alcoholic steatohepatitis-related cirrhosis: a randomised, placebo-controlled phase 2 trial

R Loomba, MF Abdelmalek, MJ Armstrong… - The Lancet …, 2023 - thelancet.com
Background Patients with non-alcoholic steatohepatitis (NASH)-related cirrhosis are at high
risk of liver-related and all-cause morbidity and mortality. We investigated the efficacy and …

GI multisociety strategic plan on environmental sustainability

H Pohl, R De Latour, A Reuben, NK Ahuja, S Gayam… - Hepatology, 2022 - journals.lww.com
PAR2 promotes impaired glucose uptake and insulin resistance... : Hepatology PAR2 promotes
impaired glucose uptake and insulin resistance in NAFLD through GLUT2 and Akt interference …

Glycemic burden and the risk of adverse hepatic outcomes in patients with chronic hepatitis B with type 2 diabetes

LY Mak, RWH Hui, CH Lee, XH Mao, KS Cheung… - Hepatology, 2023 - journals.lww.com
Glycemic burden and the risk of adverse hepatic outcomes in... : Hepatology Glycemic burden
and the risk of adverse hepatic outcomes in patients with chronic hepatitis B with type 2 …

NASHFit: A randomized controlled trial of an exercise training program to reduce clotting risk in patients with NASH

JG Stine, IR Schreibman, AJ Faust, J Dahmus… - …, 2022 - Wiley Online Library
Background and Aims NASH is a common disease associated with increased rates of
thromboembolism (TE). Although exercise training can lessen thrombotic risk in patients with …

The pan-PPAR agonist lanifibranor improves cardiometabolic health in patients with metabolic dysfunction-associated steatohepatitis

MP Cooreman, J Butler, RP Giugliano… - Nature …, 2024 - nature.com
Lanifibranor, a pan-PPAR agonist, improves liver histology in patients with metabolic
dysfunction-associated steatohepatitis (MASH), who have poor cardiometabolic health …

PAR2 promotes impaired glucose uptake and insulin resistance in NAFLD through GLUT2 and Akt interference

AM Shearer, Y Wang, EK Fletcher, R Rana… - …, 2022 - Wiley Online Library
Abstract Background and Aims Insulin resistance and poor glycemic control are key drivers
of the development of NAFLD and have recently been shown to be associated with fibrosis …

Role of insulin resistance in the development of nonalcoholic fatty liver disease in people with type 2 diabetes: from bench to patient care

JP Nogueira, K Cusi - Diabetes Spectrum, 2024 - Am Diabetes Assoc
Insulin resistance is implicated in both the pathogenesis of nonalcoholic fatty liver disease
(NAFLD) and its progression from steatosis to steatohepatitis, cirrhosis, and even …