The consumer exposure to the vast majority of cosmetic products is limited to dermal contact.
Even spray applications tend to be topically exposed to skin or hair. Besides this skin …

The induction by chemicals of allergic sensitization and allergic disease is an important and
challenging branch of toxicology. Skin sensitization resulting in allergic contact dermatitis …

Pulmonary function analysis is an important tool in the evaluation of mouse respiratory
disease models, but much controversy still exists on the validity of some tests. Most …

The recent surge in incorporation of metallic and metal oxide nanomaterials into consumer
products and their corresponding use in occupational settings have raised concerns over …

Allergic contact dermatitis is the second most commonly reported occupational illness,
accounting for 10% to 15% of all occupational diseases. This highlights the importance of …

Background Work-related health inequalities are determined to some extent by an unequal
exposure to chemical and biological risk factors of disease. Although their potential …

Exposure to particulate matter (PM) like nanoparticles (NPs) has increased in the last
century due to increased combustion processes, road traffic, etc. In addition, the progress in …

Respiratory diseases in their broad diversity need appropriate model systems to understand
the underlying mechanisms and enable development of new therapeutics. Additionally …

BACKGROUND: To assess the importance of the route of challenge in an existing mouse
model of chemical-induced asthma, we replaced intranasal instillation by oropharyngeal …

Occupational asthma can be induced by a number of chemicals at the workplace. Risk
assessment of potential sensitizers is mostly performed in animal experiments. With …