According to the 36-Item Short Form Health Survey questionnaire developers, a global
measure of health-related quality of life such as the “SF-36 Total/Global/Overall Score” …

Hyperuricemia has been recognized as an independent cardiovascular risk factor in
epidemiological studies. However, uric acid can also exert beneficial functions due to its …

Germline mutations in cellular-energy associated genes have been shown to lead to various
monogenic disorders. Notably, mitochondrial disorders often impact skeletal muscle, brain …

Objective In addition to the controversy regarding the association of hyperuricemia with
cardiovascular disease (CVD) mortality, few studies have examined the impact of a low uric …

Background Sarcopenia is a geriatric syndrome characterized by the presence of low
muscle mass and function. Possible mechanisms underlying sarcopenia include oxidative …

Background Cardiovascular disease (CVD) is the leading cause of death worldwide. Some
studies have suggested anassociation between serum uric acid levels and cardiovascular …

Background In addition to the controversy regarding the association of hyperuricemia with
mortality, uncertainty also remains regarding the association between low serum uric acid …

Background The link between elevated serum uric acid (SUA) levels and cardiovascular
disease (CVD)–related mortality in the elderly population remains inconclusive. Nutritional …

Objectives Insulin resistance (IR) has been shown to play important role in the pathogenesis
of type 2 diabetes mellitus (T2DM). There is an intricate interplay between IR, dyslipidemia …

Previous research has investigated whether hyperuricemia serves as an independent risk
factor for cardiovascular and renal diseases. Hyperuricemia is defined as an abnormally …