Immunogenic cell stress and death

G Kroemer, C Galassi, L Zitvogel, L Galluzzi - Nature immunology, 2022 - nature.com
Dying mammalian cells emit numerous signals that interact with the host to dictate the
immunological correlates of cellular stress and death. In the absence of reactive antigenic …

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

L Galluzzi, I Vitale, SA Aaronson, JM Abrams… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Cell death assays for drug discovery

O Kepp, L Galluzzi, M Lipinski, J Yuan… - Nature reviews Drug …, 2011 - nature.com
Cell death has an important role in many human diseases, and strategies aimed at
modulating the associated pathways have been successfully applied to treat various …

Current approaches for combination therapy of cancer: the role of immunogenic cell death

Z Asadzadeh, E Safarzadeh, S Safaei, A Baradaran… - Cancers, 2020 - mdpi.com
Cell death resistance is a key feature of tumor cells. One of the main anticancer therapies is
increasing the susceptibility of cells to death. Cancer cells have developed a capability of …

Bcl-2 family members: dual regulators of apoptosis and autophagy

B Levine, SC Sinha, G Kroemer - Autophagy, 2008 - Taylor & Francis
The essential autophagy protein and haplo-insufficient tumor suppressor, Beclin 1, interacts
with several cofactors (Ambra1, Bif-1, UVRAG) to activate the lipid kinase Vps34, thereby …

[HTML][HTML] Guidelines and recommendations on yeast cell death nomenclature

D Carmona-Gutierrez, MA Bauer, A Zimmermann… - Microbial Cell, 2018 - ncbi.nlm.nih.gov
Elucidating the biology of yeast in its full complexity has major implications for science,
medicine and industry. One of the most critical processes determining yeast life and …

Apoptosis in yeast: triggers, pathways, subroutines

D Carmona-Gutierrez, T Eisenberg, S Büttner… - Cell Death & …, 2010 - nature.com
A cell's decision to die is controlled by a sophisticated network whose deregulation
contributes to the pathogenesis of multiple diseases including neoplastic and …

Regulated cell death and adaptive stress responses

L Galluzzi, JM Bravo-San Pedro, O Kepp… - Cellular and Molecular …, 2016 - Springer
Eukaryotic cells react to potentially dangerous perturbations of the intracellular or
extracellular microenvironment by activating rapid (transcription-independent) mechanisms …

Entosis is induced by glucose starvation

JC Hamann, A Surcel, R Chen, C Teragawa, JG Albeck… - Cell reports, 2017 - cell.com
Entosis is a mechanism of cell death that involves neighbor cell ingestion. This process
occurs in cancers and promotes a form of cell competition, where winner cells engulf and kill …

Auto poisoning of the respiratory chain by a quorum-sensing-regulated molecule favors biofilm formation and antibiotic tolerance

R Hazan, YA Que, D Maura, B Strobel, PA Majcherczyk… - Current Biology, 2016 - cell.com
Bacterial programmed cell death and quorum sensing are direct examples of prokaryote
group behaviors, wherein cells coordinate their actions to function cooperatively like one …