OBJECTIVE: To evaluate whether vitamin D levels are related to the risk of developing
autoimmune diseases and whether supplementation with vitamin D can modify the course of …

Vitamin D has well-documented effects on calcium homeostasis and bone metabolism but
recent studies suggest a much broader role for this secosteroid in human health. Key …

Background Multiple Sclerosis is associated with low serum levels of 25-hydroxyvitamin D
(25 (OH) D). We investigated the association between serum levels of 25 (OH) D and 1, 25 …

OBJECTIVES:: We evaluated the epidemiologic evidence that vitamin D may be related to
human autoimmune disease risk. METHODS:: PubMed, limited to English from inception …

Objective: Higher latitude, lower ultraviolet exposure, and lower serum 25-hydroxyvitamin D
(25OHD) correlate with higher multiple sclerosis (MS) prevalence, relapse rate, and …

The role of hypovitaminosis D as a possible risk factor for multiple sclerosis is reviewed.
First, it is emphasized that hypovitaminosis D could be only one of the risk factors for multiple …

Background Multiple sclerosis (MS) risk is determined by both genes and environment. One
of the most striking features of MS is its geographic distribution, particularly the pattern of …

Introduction Multiple sclerosis (MS) is a chronic inflammatory disease with an as yet not fully
understood etiological background. The geographical distribution of MS is striking with a …

To estimate the associations between vitamin D status and multiple sclerosis (MS). We
searched electronic databases of the human literature in PubMed, EMBASE and the …

This review exposes recent advances on the role of vitamin D, cholecalciferol, a secosteroid,
in the central nervous system. In humans, vitamin D arises from cutaneous transformation of …