Pancreatic enzyme replacement therapy is currently the mainstay of treatment for nutrient
malabsorption secondary to pancreatic insufficiency. This treatment is safe and has few side …

Cystic fibrosis is the most common, lethal, genetic defect of white populations (1). Once
limited largely to infants and children, the immediate prognosis has changed drastically over …

The cystic fibrosis transmembrane regulator protein (CFTR) is an ion channel in the apical
surface of epithelial membranes that regulates other ion channels. Dysfunction of CFTR …

Supplemental pancreatic enzyme preparations are provided to patients with conditions of
pancreatic exocrine deficiency such as chronic pancreatitis and cystic fibrosis. These …

OBJECTIVE: The safety and efficacy of Minimicrospheres, which are enteric-coated, delayed-
release pancrelipase capsules, on fat absorption in pediatric/adolescent and adult cystic …

Standard values were established for urinary excretion and clearance of uric acid in 95
normal, nonhospitalized children. We found that urinary uric acid excretion and serum uric …

Measurement of the serum uric acid level, most commonly considered in adult patients, is
frequently obtained inadvertently for pediatric patients because it is a standard component of …

BACKGROUND:: There is a growing body of evidence regarding the association between
cystic fibrosis (CF) and nephrolithiasis and the role that Oxalobacter formigenes may have in …

Constipation and its complications, particularly meconium ileus equivalent, may become
management problems in patients with cystic fibrosis. The medical records of 168 patients …

Uric acid metabolism and renal handling in children differ distinctly from that in adults.
Serum uric acid concentrations, total urate excretion, excretion per unit of body weight, and …