[HTML][HTML] Suppressing the Aging Phenotype of Mesenchymal Stromal Cells: Are We Ready for Clinical Translation?

I Roato, M Visca, F Mussano - Biomedicines, 2024 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are involved in the maintenance and regeneration
of a large variety of tissues due to their stemness and multi-lineage differentiation capability …

Energy Metabolism and Metformin: Effects on Ischemia-Reperfusion Injury in Kidney Transplantation

DV Nemeth, L Iannelli, E Gangitano, V D'Andrea… - …, 2024 - pmc.ncbi.nlm.nih.gov
Metformin (MTF) is the only biguanide included in the World Health Organization's list of
essential medicines; representing a widespread drug in the management of diabetes …

Metformin's cardioprotective role in isoprenaline-induced myocardial infarction: Unveiling insights into the AMPK, NF-κB, JAK2/STAT3 pathways, and cholinergic …

HM El-Abasy, MEA Elsaid, EM Abdelkader… - Life Sciences, 2024 - Elsevier
Aim Despite advancements in treatment modalities, myocardial infarction (MI) remains a
significant global cause of mortality and morbidity. Metformin (MET), a commonly used …

miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosis

ZY Zhao, BX Li, DW Cheng, YF Leng - Journal of Cardiothoracic Surgery, 2025 - Springer
Background This article aims to use high-throughput sequencing to identify miRNAs
associated with ferroptosis in myocardial ischemia–reperfusion injury, select a target …

Myocardial complications induced by hypothyroidism in rats: effects of metformin and alpha lipoic acid

YA Khadrawy, EN Hosny, HS Abou-Seif… - Comparative Clinical …, 2024 - Springer
Hypothyroidism has adverse effects on heart metabolism and functions including reduced
heart rate, cardiac output and cardiac contractility. The therapeutic effects of alpha lipoic acid …

[PDF][PDF] Involvement of Oxidative Stress and Oxidants in Modification of Cardiac Dysfunction Due to Ischemia-Reperfusion Injury

NS Dhalla, P Ostadal, PS Tappia - 2025 - preprints.org
Delayed reperfusion of the ischemic heart (I/R) is known to impair recovery of cardiac
function and produce a wide variety of myocardial defects including ultrastructural damage …