Lung densitometry assesses with computed tomography (CT) the X-ray attenuation of the
pulmonary tissue which reflects both the degree of inflation and the structural lung …

Over the last decade, deep learning (DL) has contributed to a paradigm shift in computer
vision and image recognition creating widespread opportunities of using artificial …

Importance While air pollutants at historical levels have been associated with cardiovascular
and respiratory diseases, it is not known whether exposure to contemporary air pollutant …

Background Very severe chronic obstructive pulmonary disease causes cor pulmonale with
elevated pulmonary vascular resistance and secondary reductions in left ventricular filling …

OBJECTIVE. This study evaluates the relationships between quantitative CT (QCT) and
spirometric measurements of disease severity in cigarette smokers with and without chronic …

Rationale: Cigarette smoking is a risk factor for diffuse parenchymal lung disease. Risk
factors for subclinical parenchymal lung disease have not been described. Objectives: To …

Background Pulmonary emphysema is divided into 3 major subtypes at autopsy:
centrilobular, paraseptal, and panlobular emphysema. These subtypes can be defined by …

Background Interstitial lung disease (ILD) is associated with high morbidity and mortality in
rheumatoid arthritis (RA). Citrullinated proteins are observed in RA lung tissues; however …

Evidence suggests that lung injury, inflammation and extracellular matrix remodelling
precede lung fibrosis in interstitial lung disease (ILD). We examined whether a quantitative …

Abstract The Multi-Ethnic Study of Atherosclerosis and Air Pollution (MESA Air) was initiated
in 2004 to investigate the relation between individual-level estimates of long-term air …