In the intact organism, ischemic myocardial injury initiates an acute inflammatory response
in which polymorphonuclear leukocytes (PMNs) are major participants. Evidence indicates …

The relevance of cyclooxygenases (COX)-1 and-2 and their products to inflammation,
thrombosis and gastroprotection are well known. Their importance in the immune response …

The O2−-forming NADPH oxidase of the phagocytes: nature, mechanisms of activation and
function - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

Understanding the pathogenesis of the Adult Respiratory Distress Syndrome (ARDS) is a
major goal of pulmonary research. This emphasis is appropriate because it has been …

Granulocyte (PMN) aggregation and embolization may underlie complement (C)-mediated
organ dysfunction in such syndromes as hemodialysis neutropenia and Purtscher's ischem; …

Physical interaction of T cells and dendritic cells (DCs) is essential for T cell proliferation and
differentiation, but it has been unclear how this interaction is regulated physiologically. Here …

Current dogma holds that nonsteroidal anti-inflammatory drugs (NSAIDs) act by inhibition of
the synthesis and release of prostaglandins. However, NSAIDs also inhibit the activation of …

Thromboxane synthase from human platelets was purified to apparent homogeneity by
conventional chromatographic techniques. A 423-fold enrichment over the specific content …

[14C] Arachidonic acid incubated with human neutrophils was esterified into phospholipids
and triglycerides. Stimulation of these labeled neutrophils with ionophore A23187 (2 …

Dual radiolabel incorporation of [3H] arachidonic acid and [14C] palmitate or [14C] stearate
by human neutrophils was employed to study both the release and metabolism of …