Toward the early detection of cancer by decoding the epigenetic and environmental fingerprints of cell-free DNA

Y Van Der Pol, F Mouliere - Cancer cell, 2019 - cell.com
Widespread adaptation of liquid biopsy for the early detection of cancer has yet to reach
clinical utility. Circulating tumor DNA is commonly detected though the presence of genetic …

Telling plant species apart with DNA: from barcodes to genomes

PM Hollingsworth, DZ Li… - … Transactions of the …, 2016 - royalsocietypublishing.org
Land plants underpin a multitude of ecosystem functions, support human livelihoods and
represent a critically important component of terrestrial biodiversity—yet many tens of …

Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars

G Hu, J Feng, X Xiang, J Wang, J Salojärvi, C Liu… - Nature …, 2022 - nature.com
Lychee is an exotic tropical fruit with a distinct flavor. The genome of cultivar 'Feizixiao'was
assembled into 15 pseudochromosomes, totaling~ 470 Mb. High heterozygosity (2.27%) …

MitoFinder: Efficient automated large‐scale extraction of mitogenomic data in target enrichment phylogenomics

R Allio, A Schomaker‐Bastos… - Molecular ecology …, 2020 - Wiley Online Library
Thanks to the development of high‐throughput sequencing technologies, target enrichment
sequencing of nuclear ultraconserved DNA elements (UCEs) now allows routine inference …

MitoZ: a toolkit for animal mitochondrial genome assembly, annotation and visualization

G Meng, Y Li, C Yang, S Liu - Nucleic acids research, 2019 - academic.oup.com
Mitochondrial genome (mitogenome) plays important roles in evolutionary and ecological
studies. It becomes routine to utilize multiple genes on mitogenome or the entire …

A reference genome for pea provides insight into legume genome evolution

J Kreplak, MA Madoui, P Cápal, P Novák, K Labadie… - Nature …, 2019 - nature.com
We report the first annotated chromosome-level reference genome assembly for pea, Gregor
Mendel's original genetic model. Phylogenetics and paleogenomics show genomic …

GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes

JJ Jin, WB Yu, JB Yang, Y Song, CW DePamphilis… - Genome biology, 2020 - Springer
GetOrganelle is a state-of-the-art toolkit to accurately assemble organelle genomes from
whole genome sequencing data. It recruits organelle-associated reads using a modified …

NOVOPlasty: de novo assembly of organelle genomes from whole genome data

N Dierckxsens, P Mardulyn, G Smits - Nucleic acids research, 2017 - academic.oup.com
The evolution in next-generation sequencing (NGS) technology has led to the development
of many different assembly algorithms, but few of them focus on assembling the organelle …

Genomes of subaerial Zygnematophyceae provide insights into land plant evolution

S Cheng, W Xian, Y Fu, B Marin, J Keller, T Wu, W Sun… - Cell, 2019 - cell.com
The transition to a terrestrial environment, termed terrestrialization, is generally regarded as
a pivotal event in the evolution and diversification of the land plant flora that changed the …

Fern genomes elucidate land plant evolution and cyanobacterial symbioses

FW Li, P Brouwer, L Carretero-Paulet, S Cheng… - Nature plants, 2018 - nature.com
Ferns are the closest sister group to all seed plants, yet little is known about their genomes
other than that they are generally colossal. Here, we report on the genomes of Azolla …