Cytokine-polymorphisms associated with Preeclampsia: A review

C Mora-Palazuelos, M Bermúdez, M Aguilar-Medina… - Medicine, 2022 - journals.lww.com
Background: Preeclampsia (PE) is a syndromic disorder that affects 2% to 8% of
pregnancies and is diagnosed principally when hypertension appears in the second-d half …

Emerging roles of growth factors in osteonecrosis of the femoral head

Z Che, Y Song, L Zhu, T Liu, X Li, L Huang - Frontiers in Genetics, 2022 - frontiersin.org
Osteonecrosis of the femoral head (ONFH) is a potentially disabling orthopedic condition
that requires total hip arthroplasty in most late-stage cases. However, mechanisms …

Analysis of VEGFA Variants and Changes in VEGF Levels Underscores the Contribution of VEGF to Polycystic Ovary Syndrome

WY Almawi, E Gammoh, ZH Malalla, SA Al-Madhi - PloS one, 2016 - journals.plos.org
Background Vascular endothelial growth factor (VEGF) contributes to the pathogenesis of
polycystic ovary syndrome (PCOS), and genetic variations in VEGFA gene were suggested …

MTHFR and F5 genetic variations have association with preeclampsia in Pakistani patients: a case control study

FF Khidri, YM Waryah, FK Ali, H Shaikh, ID Ujjan… - BMC medical …, 2019 - Springer
Background To study the role of single nucleotide variants (SNVs) of genes related to
preeclampsia in Pakistani pregnant women. Methods After ethical approval and getting …

Vascular endothelial growth factor+ 936C/T,–634G/C,–2578C/a, and–1154G/a polymorphisms with risk of preeclampsia: a meta-analysis

D Cheng, Y Hao, W Zhou, Y Ma - PLoS One, 2013 - journals.plos.org
Background Emerging evidence showed that VEGF gene polymorphisms are involved in the
regulation of VEGF protein expression, thus increasing an individual's susceptibility to …

VEGF-A and VEGFR1 SNPs associate with preeclampsia in a Philippine population

MD Amosco, VAM Villar, JMA Naniong… - Clinical and …, 2016 - Taylor & Francis
The vascular endothelial growth factor (VEGF) family is important for establishing normal
pregnancy, and related single nucleotide polymorphisms (SNPs) are implicated in abnormal …

Analysis of VEGF gene polymorphisms and serum VEGF protein levels contribution in polycystic ovary syndrome of patients

L Bao, R Syed, MS Aloahd - Molecular biology reports, 2019 - Springer
Vascular endothelial growth factor (VEGF) is a well-known factor in reproductive function
and contributes to the pathogenesis of polycystic ovary syndrome (PCOS). Genetic …

Early-and late-onset preeclampsia and the DNA methylation of circadian clock and clock-controlled genes in placental and newborn tissues

CB Van den Berg, I Chaves, EM Herzog… - Chronobiology …, 2017 - Taylor & Francis
The placenta is important in providing a healthy environment for the fetus and plays a central
role in the pathophysiology of preeclampsia (PE). Fetal and placental developments are …

Vascular endothelial growth factor (VEGF)‐634G/C polymorphism was associated with severe pre‐eclampsia and lower serum VEGF level

S Salimi, M Yaghmaei, E Tabatabaei… - Journal of Obstetrics …, 2015 - Wiley Online Library
Aim Vascular endothelial growth factor (VEGF) is an angiogenic factor whose production is
increased in pre‐eclampsia (PE). Therefore, the present study was conducted aiming at …

Association between vascular endothelial growth factor gene polymorphisms and pre-eclampsia susceptibility: an updated meta-analysis

X Wang, T Sun, G Chen, H Gao - Immunological investigations, 2020 - Taylor & Francis
Objectives: The aim of this study was to assess the genetic association between vascular
endothelial growth factor (VEGF) gene polymorphisms and the risk of pre-eclampsia (PE) …