A comprehensive metabolic map for production of bio-based chemicals
Production of industrial chemicals using renewable biomass feedstock is becoming
increasingly important to address limited fossil resources, climate change and other …
increasingly important to address limited fossil resources, climate change and other …
Cell‐free metabolic engineering: biomanufacturing beyond the cell
Industrial biotechnology and microbial metabolic engineering are poised to help meet the
growing demand for sustainable, low‐cost commodity chemicals and natural products, yet …
growing demand for sustainable, low‐cost commodity chemicals and natural products, yet …
[HTML][HTML] RetroPath2. 0: a retrosynthesis workflow for metabolic engineers
Synthetic biology applied to industrial biotechnology is transforming the way we produce
chemicals. However, despite advances in the scale and scope of metabolic engineering, the …
chemicals. However, despite advances in the scale and scope of metabolic engineering, the …
Basic and applied uses of genome‐scale metabolic network reconstructions of Escherichia coli
D McCloskey, BØ Palsson, AM Feist - Molecular systems biology, 2013 - embopress.org
The genome‐scale model (GEM) of metabolism in the bacterium Escherichia coli K‐12 has
been in development for over a decade and is now in wide use. GEM‐enabled studies of E …
been in development for over a decade and is now in wide use. GEM‐enabled studies of E …
Predictive design of mRNA translation initiation region to control prokaryotic translation efficiency
Precise prediction of prokaryotic translation efficiency can provide valuable information for
optimizing bacterial host for the production of biochemical compounds or recombinant …
optimizing bacterial host for the production of biochemical compounds or recombinant …
Bioprivileged molecules: creating value from biomass
BH Shanks, PL Keeling - Green Chemistry, 2017 - pubs.rsc.org
The petrochemical industry is built on C2–C4 alkenes and aromatics as intermediate
molecules, which are converted to a range of products. This industry is highly developed …
molecules, which are converted to a range of products. This industry is highly developed …
Biosynthesis and synthetic biology of psychoactive natural products
Psychoactive natural products play an integral role in the modern world. The tremendous
structural complexity displayed by such molecules confers diverse biological activities of …
structural complexity displayed by such molecules confers diverse biological activities of …
[HTML][HTML] Multi-omics and metabolic modelling pipelines: challenges and tools for systems microbiology
Integrated-omics approaches are quickly spreading across microbiology research labs,
leading to (i) the possibility of detecting previously hidden features of microbial cells like …
leading to (i) the possibility of detecting previously hidden features of microbial cells like …
Progress toward improving ethanol production through decreased glycerol generation in Saccharomyces cerevisiae by metabolic and genetic engineering …
Bioethanol, a prominent biofuel mostly produced industrially by the yeast Saccharomyces
cerevisiae, has been among the main pillars of sustainable development in the …
cerevisiae, has been among the main pillars of sustainable development in the …
Multivariate modular metabolic engineering for pathway and strain optimization
Highlights•The rationale and underlying principles of multivariate modular metabolic
engineering (MMME) are given.•Several examples highlighting MMME's pathway …
engineering (MMME) are given.•Several examples highlighting MMME's pathway …