Methods for the diagnosis of infectious diseases have stagnated in the last 20–30 years.
Few major advances in clinical diagnostic testing have been made since the introduction of …

Lymphatic filariasis (LF) is a disease not just treatable or controllable; it is a disease that can
be eliminated. Indeed, LF is currently the target of a major global initiative to do just that; a …

The ambitious and exciting Global Programme to Eliminate Lymphatic Filariasis (GPELF) is
largely based on a strategy of mass drug administration (MDA) of repeated rounds of …

Diagnostic tools appropriate for undertaking interventions to control helminth infections are
key to their success. Many diagnostic tests for helminth infection have unsatisfactory …

Accurate detection of filarial parasites in humans is essential for the implementation and
evaluation of mass drug administration programs to control onchocerciasis and lymphatic …

Background Egypt was one of the first countries to implement a national programme to
eliminate lymphatic filariasis based on WHO's strategy of repeated rounds of mass drug …

The morphologic similarities of the microfilariae and their infrequency in clinical specimens
in settings of endemicity present challenges to clinical laboratories in maintaining …

We developed and evaluated real-time polymerase chain reaction (PCR) assays for
detecting Wuchereria bancrofti DNA in human blood and in mosquitoes. An assay based on …

MicroRNAs have been shown to contribute to a repertoire of host-pathogen interactions
during viral infection. Our previous study demonstrated that microRNA-30e*(miR-30e*) …

Background Control and elimination strategies for trachoma, lymphatic filariasis,
onchocerciasis, schistosomiasis, ascariasis, trichuriasis and hookworm infection have …