A major goal of evolutionary genetics is to understand the genetic processes that give rise to
phenotypic diversity in multicellular organisms. Alternative splicing generates multiple …

RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …

High-throughput sequencing-based methods and their applications in the study of
transcriptomes have revolutionized our understanding of alternative splicing. Networks of …

Abstract N6‑methyladenosine (m6A) is the most prevalent and abundant type of internal post‑
transcriptional RNA modification in eukaryotic cells. Multiple types of RNA, including …

To date, a large number of long non-coding RNAs (lncRNAs) have been recently discovered
through functional genomics studies. Importantly, lncRNAs have been shown, in many …

Most human genes have multiple sites at which RNA 3ʹ end cleavage and polyadenylation
can occur, enabling the expression of distinct transcript isoforms under different conditions …

Transposable elements are abundant in the human genome, and great strides have been
made in pinpointing variations in these repetitive sequences using whole-genome …

Abstract N6-methyladenosine (m6A) is methylation that occurs in the N6-position of
adenosine, which is the most prevalent internal modification on eukaryotic mRNA …

RNA-binding proteins control many aspects of cellular biology through binding single-
stranded RNA binding motifs (RBMs),,. However, RBMs can be buried within their local RNA …

Transposable element (TE)-derived sequences are ubiquitous in most eukaryotic genomes
known to date. Because their expression and mobility can lead to genomic instability …