Female Aedes aegypti mosquitoes infect more than 400 million people each year with
dangerous viral pathogens including dengue, yellow fever, Zika and chikungunya. Progress …

Helitrons are one of three groups of eukaryotic class 2 transposable elements (TEs) so far
described. Unique in structure and coding capacity, they are hypothesized to move by a …

Hox genes code for transcription factors and are evolutionarily conserved. They regulate a
plethora of downstream targets to define the anterior-posterior (AP) body axis of a …

Comparative analysis of multiple genomes in a phylogenetic framework dramatically
improves the precision and sensitivity of evolutionary inference, producing more robust …

Summary In Drosophila melanogaster, Hox genes are organized in an anterior and a
posterior cluster, called Antennapedia complex and bithorax complex, located on the same …

Background Hox genes were critical to many morphological innovations of bilaterian
animals. However, early Hox evolution remains obscure. Phylogenetic, developmental, and …

While the highly consistent gene order and axial colinear patterns of expression seem to be
a feature of vertebrate hox gene clusters, this pattern may be less well conserved across the …

The cephalochordate amphioxus is the closest living invertebrate relative of the vertebrates.
It is vertebrate-like in having a dorsal, hollow nerve cord, notochord, segmental muscles …

Chromosome rearrangements may distort 3D chromatin architectures and thus change gene
regulation, yet how 3D chromatin structures evolve in insects is largely unknown. Here, we …

Hox genes are known to specify spatial identities along the anterior-posterior axis during
embryogenesis. In vertebrates and most other deuterostomes, they are arranged in sets of …