During the last decade, experimental and clinical studies have demonstrated that isolated
acute brain injury (ABI) may cause severe dysfunction of peripheral extracranial organs and …

Abstract The coronavirus disease-19 (COVID-19) pandemic is an unprecedented worldwide
health crisis. COVID-19 is caused by SARS-CoV-2, a highly infectious pathogen that is …

Purpose To provide clinical practice recommendations and generate a research agenda on
mechanical ventilation and respiratory support in patients with acute brain injury (ABI) …

Background In COVID-19 patients with acute respiratory distress syndrome (ARDS), the
effectiveness of ventilatory rescue strategies remains uncertain, with controversial efficacy …

To ensure neuronal survival after severe traumatic brain injury, oxygen supply is essential.
Cerebral tissue oxygenation represents the balance between oxygen supply and …

Objectives Acute respiratory distress syndrome (ARDS) in patients with traumatic brain injury
(TBI) is associated with increased mortality. Information on the prevalence of ARDS and its …

Abstract Approximately 20–25% of traumatic brain injury (TBI) subjects develop acute lung
injury (ALI), but the pathomechanisms of TBI-induced ALI remain poorly defined. Our …

Patients with traumatic brain injury (TBI) frequently require invasive mechanical ventilation
and admission to an intensive care unit. Ventilation of patients with TBI poses unique clinical …

Many neurological diseases may cause acute respiratory failure (ARF) due to involvement of
bulbar respiratory center, spinal cord, motoneurons, peripheral nerves, neuromuscular …

Neuropatients often require invasive mechanical ventilation (MV). Ideal ventilator settings
and respiratory targets in neuro patients are unclear. Current knowledge suggests …