Post-translational modifications (PTMs) are chemical modifications that can regulate the
activity and function of proteins. From an evolutionary perspective, they also represent a fast …

Over the past decades, our understanding of microbial metabolism has increased
dramatically. Metabolomics, a family of techniques that are used to measure the quantities of …

Advanced mass spectrometry methods have detected thousands of post-translational
phosphorylation and acetylation sites in bacteria, but their functional role and the enzymes …

Post‐translational modifications (PTMs) play an essential role in most biological processes.
PTMs on human proteins have been extensively studied. Studies on bacterial PTMs are …

Reactions involving the transfer of phosphorus-containing groups are of key importance for
maintaining life, from biological cells, tissues and organs to plants, animals, humans …

Native mass spectrometry (nMS) is becoming a crucial tool for analyzing membrane proteins
(MPs), yet challenges remain in solubilizing and stabilizing their native conformations while …

Highlights•PTMs are emerging as key actors during phage infection.•Bioinformatics-driven
screens can identify new PTM enzymes in phage and bacteria.•Improved mass spectrometry …

Phosphosignaling in bacteria is mediated by two distinct systems, the two-component
systems (TCSs) and the protein Ser/Thr/Tyr, or O-phosphorylation systems. These two arms …

The protein activator of protein kinase R (PKR)(PACT) has been shown to play a crucial role
in stimulating the host antiviral response through the activation of PKR, retinoic acid …

Streptococcus pyogenes (Group A Streptococcus/GAS or S. pyogenes) is endowed with a
formidable arsenal of virulence factors that allow it to evade host's innate immune responses …