Exosomes are small nanosized biovesicles that form when multivesicular bodies and the
plasma membrane fuse and are released into the surrounding body fluids. They are best …

Drug delivery to the central nervous system (CNS) is limited due to the presence of the blood–
brain barrier (BBB), a selective physiological barrier located at the brain microvessels that …

Alzheimer's disease (AD) is a degenerative disease that causes memory and learning
impairments as well as dementia. Coenzyme Q10 (CoQ10) is an anti-inflammatory and anti …

Extracellular vesicles (EVs) are lipid bilayer membrane particles that play critical roles in
intracellular communication through EV-encapsulated informative content, including …

Exosomes are nanoscale extracellular vesicles secreted by cells and enclosed by a lipid
bilayer membrane containing various biologically active cargoes such as proteins, lipids …

Introduction Objective and accessible markers for Alzheimer's disease (AD) and other
dementias are critically needed. Methods We identified NMDAR2A, a protein related to …

With the increasing number of patients suffering from central nervous system (CNS)
diseases, there is a pressing demand to acquire dependable diagnostic tools in the early …

Stroke is a leading cause of death and disability in the world. Astrocytes are special glial
cells within the central nervous system and play important roles in mediating …

Shuttling various bioactive substances across the blood–brain barrier (BBB) bidirectionally,
extracellular vesicles (EVs) have been opening new frontiers for the diagnosis and therapy …

Exosomes, as potent intercellular communication tools, have garnered significant attention
due to their unique cargo-carrying capabilities, which enable them to influence diverse …