Dynamics of DNA methylation and its functions in plant growth and development

S Kumar, T Mohapatra - Frontiers in Plant Science, 2021 - frontiersin.org
Epigenetic modifications in DNA bases and histone proteins play important roles in the
regulation of gene expression and genome stability. Chemical modification of DNA base …

DNA methylation and schizophrenia: current literature and future perspective

T Magwai, KB Shangase, FO Oginga, B Chiliza… - Cells, 2021 - mdpi.com
Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …

Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex

GL Shireby, JP Davies, PT Francis, J Burrage… - Brain, 2020 - academic.oup.com
Human DNA methylation data have been used to develop biomarkers of ageing, referred to
as 'epigenetic clocks', which have been widely used to identify differences between …

Evolution of DNA methylation in the human brain

H Jeong, I Mendizabal, S Berto, P Chatterjee… - Nature …, 2021 - nature.com
DNA methylation is a critical regulatory mechanism implicated in development, learning,
memory, and disease in the human brain. Here we have elucidated DNA methylation …

The role of DNA methylation in ageing and cancer

AE Morgan, TJ Davies, MT Mc Auley - Proceedings of the Nutrition …, 2018 - cambridge.org
The aim of the present review paper is to survey the literature related to DNA methylation,
and its association with cancer and ageing. The review will outline the key factors, including …

Comparative pan-cancer DNA methylation analysis reveals cancer common and specific patterns

X Yang, L Gao, S Zhang - Briefings in bioinformatics, 2017 - academic.oup.com
Abnormal DNA methylation is an important epigenetic regulator involving tumorigenesis.
Deciphering cancer common and specific DNA methylation patterns is essential for us to …

Cell type-specific epigenetic links to schizophrenia risk in the brain

I Mendizabal, S Berto, N Usui, K Toriumi, P Chatterjee… - Genome biology, 2019 - Springer
Background The importance of cell type-specific epigenetic variation of non-coding regions
in neuropsychiatric disorders is increasingly appreciated, yet data from disease brains are …

Evolutionary transition of promoter and gene body DNA methylation across invertebrate–vertebrate boundary

TE Keller, P Han, SV Yi - Molecular biology and evolution, 2016 - academic.oup.com
Genomes of invertebrates and vertebrates exhibit highly divergent patterns of DNA
methylation. Invertebrate genomes tend to be sparsely methylated, and DNA methylation is …

Characterization of DNA methylation-based markers for human body fluid identification in forensics: a critical review

F Kader, M Ghai, AO Olaniran - International journal of legal medicine, 2020 - Springer
Body fluid identification in crime scene investigations aids in reconstruction of crime scenes.
Several studies have identified and reported differentially methylated sites (DMSs) and …

Insights into S-adenosyl-l-methionine (SAM)-dependent methyltransferase related diseases and genetic polymorphisms

J Li, C Sun, W Cai, J Li, BP Rosen, J Chen - Mutation Research/Reviews in …, 2021 - Elsevier
Enzymatic methylation catalyzed by methyltransferases has a significant impact on many
human biochemical reactions. As the second most ubiquitous cofactor in humans, S …